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Effects of Sahaj Samadhi meditation on heart rate variability and depressive symptoms in patients with late-life depression.

The British journal of psychiatry : the journal of mental science
April 1, 2019
Emily Ionson et al. (8 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to assess the efficacy of Sahaj Samadhi meditation (SSM) on heart rate variability (HRV) and depressive symptoms in older adults with mild to moderate depression.

Results Summary

SSM significantly improved depressive symptoms compared to treatment as usual (TAU), but did not significantly improve HRV. The improvement in depressive symptoms was statistically significant, though HRV measures remained unchanged.

Population

Men and women aged 60-85 years with mild to moderate depression.

Effective Dosage

4 consecutive days of group meditation training followed by 11 weekly reinforcement sessions.

Duration

12 weeks.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Sahaj Samadhi meditation (SSM)
no change
All time and frequency domain measures of HRV
men and women aged 60-85 years, with mild to moderate depression and receiving treatment as usual (TAU)
no significant change
did not significantly change
#1
Sahaj Samadhi meditation (SSM)
decrease
Hamilton Rating Scale for Depression (HRSD; 17-item) score
men and women aged 60-85 years, with mild to moderate depression and receiving treatment as usual (TAU)
difference in mean, 2.66; 95% CI 0.26-5.05; P = 0.03
significant improvement
#2
Sahaj Samadhi meditation (SSM)
decrease
depressive symptoms
patients with LLD
-
is associated with improvements
#3
Sahaj Samadhi meditation (SSM)
no change
HRV
patients with LLD
-
does not significantly improve
#4
Abstract

BACKGROUND: Late-life depression (LLD) is a disabling disorder and antidepressants are ineffective in as many as 60% of cases. Converging evidence shows a strong correlation between LLD and subsequent risk of cardiovascular disease. There is a need for new, well-tolerated, non-pharmacological augmentation interventions that can treat depressive symptoms as well as improve heart rate variability (HRV), an important prognostic marker for development of subsequent cardiovascular disease. Meditation-based techniques are of interest based on positive findings in other samples.AimsWe aimed to assess the efficacy of Sahaj Samadhi meditation (SSM), an underevaluated, standardised and manualised meditation intervention, on HRV and depressive symptoms. METHOD: Eighty-three men and women aged 60-85 years, with mild to moderate depression and receiving treatment as usual (TAU) were randomised to either the SSM or TAU arm. Those allocated to SSM attended 4 consecutive days of group meditation training, using personalised mantras followed by 11 weekly reinforcement sessions. HRV and Hamilton Rating Scale for Depression (HRSD; 17-item) score were measured at baseline and 12 weeks. RESULTS: All time and frequency domain measures of HRV did not significantly change in either arm. However, there was significant improvement in the SSM arm, compared with TAU, on the HRSD (difference in mean, 2.66; 95% CI 0.26-5.05; P = 0.03). CONCLUSIONS: Compared with TAU, SSM is associated with improvements in depressive symptoms but does not significantly improve HRV in patients with LLD. These results need to be replicated in subsequent studies incorporating a group-based, active control arm.Declaration of interestR.I.N. is the Director of Research and Health Promotion for the Art of Living Foundation, Canada and supervised the staff providing Sahaj Samadhi meditation. S.R. has received research funding from Satellite Healthcare for a mindfulness meditation trial in patients on haemodialysis. The remaining authors report no financial or other relationship relevant to the subject of this article.

Medical Subject Headings (MeSH)
AgedAged, 80 and overDepressionFemaleHeart RateHumansMaleMeditationMiddle AgedOntarioPsychiatric Status Rating ScalesQuality of LifeSelf Care
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality75/10
Citation Metrics
Total Citations15
Citations/Year2.5
Relative Citation Ratio1.29
NIH Percentile59.7%
Research Impact Scores
APT Score0.75
Weight Score2.14
Normalized Score0.61
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