Vertebral spine osteoporosis treatment efficacy in local population: A clinical study.
Study Goal
The researchers aimed to determine the efficacy of calcium and vitamin D3 supplementation in treating vertebral spine osteoporosis in a local Pakistani population.
Results Summary
The study found no reduction in T-scores with calcium and vitamin D3 supplementation, suggesting no significant improvement in vertebral osteoporosis. The findings do not support routine oral supplementation for osteoporosis treatment.
Population
Pakistani individuals with vertebral spine osteoporosis.
Effective Dosage
1250 mg Calcium and 125 IU Cholecalciferol, twice daily.
Duration
6 months
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
calcium and vitamin D3 administration | no change | T-score | individuals with vertebral spine osteoporosis | - | no reduction | #1 |
calcium and vitamin D3 administration | decrease | T-score | individuals with vertebral spine osteoporosis | - | reduction | #2 |
Tabs Chewable: Calcium: 1250 mg, Cholecalciferol: 125 IU, BD/Day | neutral | mean T-score before treatment | individuals with vertebral spine osteoporosis | 2.890 ±1.7217 | recorded | #3 |
Tabs Chewable: Calcium: 1250 mg, Cholecalciferol: 125 IU, BD/Day | neutral | mean T-score after treatment | individuals with vertebral spine osteoporosis | -2.456±0.8064 | recorded | #4 |
calcium and vitamin D3 orally | no change | osteoporosis | individuals with vertebral spine osteoporosis | - | do not provide support for routine supplementation | #5 |
In Pakistani population the prevalence of Calcium and vitamin D deficiency is at alarming rate. Previous studies show that globally vertebral osteoporosis is most commonly recognized site causing deterioration to personal life satisfaction. It is very unfortunate that in Pakistan ample amount of research work has not been done in the area, consequently, information on rate of vertebral osteoporosis & fracture are rare in Pakistan. There is no reduction in T-score on supplementation with calcium and vitamin D3 administration. There is reduction in T-score on supplementation with calcium and vitamin D3 administration. The prime objective of the current work was to determine vertebral spine osteoporosis treatment efficacy in local population. This is an intervention experimental study with no control. The study population was selected from the local community; consisting of individuals with vertebral spine osteoporosis, further they were followed for up to 6 months. Data was analyzed by SPSS-22. Tabs Chewable: Calcium: 1250 mg, Cholecalciferol: 125 IU, BD/Day was advised. The mean T-score before and after treatment were recorded as; Mean ±S.D: 2.890 ±1.7217 and Mean ±S.D: -2.456±0.8064 respectively. The findings of the current work do not provide support for routine supplementation with calcium and vitamin D3 orally for osteoporosis.