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Benefits of mindfulness meditation in reducing blood pressure and stress in patients with arterial hypertension.

Journal of human hypertension
March 1, 2019
Paola Helena Ponte Márquez et al. (9 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the benefits of mindfulness meditation on controlling ambulatory blood pressure and its impact on anxiety, stress, and depression levels in a Mediterranean population with high-normal BP or grade I hypertension.

Results Summary

The mindfulness group showed statistically significant lower ambulatory and clinically measured blood pressure values by week 8, along with improvements in being less judgmental, more accepting, and less depressed. At week 20 follow-up, means were lower in the intervention group, though not statistically significant.

Population

Mediterranean adults (mean age 56.5 years) with high-normal BP or grade I hypertension, including similar proportions of men and women.

Effective Dosage

2 hours per week for 8 weeks

Duration

8 weeks (with follow-up at week 20)

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness meditation
decrease
ambulatory blood pressure (BP)
Mediterranean population with high-normal BP or grade I hypertension
-
lower
#1
mindfulness meditation
neutral
anxiety, stress and depression levels
Mediterranean population with high-normal BP or grade I hypertension
-
impact on
#2
mindfulness training
decrease
ABPM scores
intervention group
124/77 mmHg vs 126/80 mmHg (p < 0.05) for 24-h systolic BP
statistically significant lower
#3
mindfulness training
decrease
ABPM scores
intervention group
108/65 mmHg vs 114/69 mmHg (p < 0.05) for night-time systolic BP
statistically significant lower
#4
mindfulness training
decrease
clinically measured SBP values
intervention group
130 mmHg vs 133 mmHg; p = 0.02
lower
#5
mindfulness training
decrease
-
intervention group
although not statistically significant
means were lower
#6
mindfulness training
increase
being less judgemental, more accepting and less depressed
intervention group
-
Improvements were observed
#7
Abstract

The objective of this randomized controlled trial is to evaluate the benefits of mindfulness meditation in controlling ambulatory blood pressure (BP) and the impact of the intervention on anxiety, stress and depression levels in a Mediterranean population. Twenty-four and 18 patients [n = 42; mean age 56.5 (7.7) years; similar men and women proportions] with high-normal BP or grade I hypertension were enrolled to an intervention and a control group, respectively. For 2 h/week over 8 weeks, the intervention group received mindfulness training and the control group attended health education talks. The patients attended pre-intervention, week 4, week 8 and week 20 follow-up visits. 61.9% of the patients had anxiety, 21.4% depression, 19.0% were smokers and 14.2% were diabetic (no significant differences between the 2 groups). At baseline, the intervention group had non-significant higher clinically measured BP values, whereas both groups had similar ambulatory BP monitoring (ABPM) values. At week 8, the intervention group had statistically significant lower ABPM scores than the control group (124/77 mmHg vs 126/80 mmHg (p < 0.05) and 108/65 mmHg vs 114/69 mmHg (p < 0.05) for 24-h and night-time systolic BP (SBP), respectively) and also had lower clinically measured SBP values (130 mmHg vs 133 mmHg; p = 0.02). At week 20 (follow-up), means were lower in the intervention group (although not statistically significant). Improvements were observed in the intervention group in terms of being less judgemental, more accepting and less depressed. In conclusion, by week 8 the mindfulness group had lower clinically measured SBP, 24-h SBP, at-rest SBP and diastolic BP values.

Medical Subject Headings (MeSH)
Blood PressureFemaleHumansHypertensionMaleMeditationMiddle AgedMindfulnessProspective StudiesStress, Psychological
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations43
Citations/Year7.2
Relative Citation Ratio2.95
NIH Percentile84.6%
Research Impact Scores
APT Score0.95
Weight Score2.31
Normalized Score0.69
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