Non-Invasive Ventilation as an Adjunct to Exercise Training in Chronic Ventilatory Failure: A Narrative Review.
Study Goal
The researchers aimed to determine whether non-invasive ventilation (NIV) during walking could improve exercise tolerance, oxygenation, and walking distance in patients with chronic ventilatory failure (CVF).
Results Summary
The study found that NIV during walking improved oxygenation, reduced dyspnea, and increased walking distance in patients with CVF. Different NIV modalities and interfaces were effective during exercise training.
Population
Patients with chronic ventilatory failure (CVF) on long-term non-invasive ventilation (NIV).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Long-term non-invasive ventilation (NIV) | decrease | patients' symptoms | patients with chronic ventilatory failure | - | may reduce | #1 |
Long-term non-invasive ventilation (NIV) | increase | health-related quality of life | patients with chronic ventilatory failure | - | improve | #2 |
Long-term non-invasive ventilation (NIV) | decrease | mortality and hospitalisations | patients with chronic ventilatory failure | - | reduce | #3 |
NIV during exercise training | increase | exercise intensity | patients with chronic ventilatory failure | - | train patients at intensity levels higher than allowed | #4 |
Exercise training | increase | exercise capacity | patients with chronic ventilatory failure | - | feasible and effective | #5 |
Assisted ventilation | increase | exercise tolerance | patients with different clinical conditions | - | improve | #6 |
NIV administered during walking | increase | oxygenation | patients under long-term home ventilatory support | - | improved | #7 |
NIV administered during walking | decrease | dyspnoea | patients under long-term home ventilatory support | - | decreased | #8 |
NIV administered during walking | increase | walking distance | patients under long-term home ventilatory support | - | increased | #9 |
exercising with the same ventilators, interfaces and settings as used at home | increase | exercise outcomes | patients with chronic ventilatory failure on long-term NIV | - | may benefit from | #10 |
BACKGROUND: Chronic ventilatory failure (CVF) may be associated with reduced exercise capacity. Long-term non-invasive ventilation (NIV) may reduce patients' symptoms, improve health-related quality of life and reduce mortality and hospitalisations. There is an increasing use of NIV during exercise training with the purpose to train patients at intensity levels higher than allowed by their pathophysiological conditions. OBJECTIVE: This narrative review describes the possibility to train patients with CVF and NIV use as a tool to increase the benefits of exercise training. METHODS: We searched papers published between 1985 and 2018 in (or with the summary in) English language in PubMed and Scopus databases using the keywords "chronic respiratory failure AND exercise," "non invasive ventilation AND exercise," "pulmonary rehabilitation" and "exercise training." RESULTS: Exercise training is feasible and effective also in patients with CVF. Assisted ventilation can improve exercise tolerance in different clinical conditions. In patients under long-term home ventilatory support, NIV administered also during walking results in improved oxygenation, decreased dyspnoea and increased walking distance. Continuous positive airway pressure and different modalities of assisted ventilation have been delivered through different interfaces during exercise training programmes. Patients with CVF on long-term NIV may benefit from exercising with the same ventilators, interfaces and settings as used at home. CONCLUSION: We need more randomised clinical trials to investigate the effects of NIV on exercise training in patients with CVF and define organisation and setting.