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Qigong intervention for breast cancer survivors with complaints of decreased cognitive function.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
April 1, 2019
Jamie S Myers et al. (12 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the feasibility and cognitive benefits of an 8-week Qigong intervention compared to gentle exercise and survivorship support in breast cancer survivors post-treatment.

Results Summary

Qigong showed the most improvement in self-reported cognitive function and distress reduction, though adherence rates were lower than targeted. Gentle exercise and support groups also demonstrated some cognitive improvements in specific tests.

Population

Breast cancer survivors 2 months to 8 years post-chemotherapy and radiation therapy.

Effective Dosage

8-week Qigong intervention (specific frequency not detailed).

Duration

8 weeks, with follow-up at 4 weeks post-intervention.

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Qigong intervention
increase
self-report of cognitive function
breast cancer survivors
-
improved most
#1
gentle exercise
increase
Trail Making A test
breast cancer survivors
-
improvement was demonstrated
#2
support group
increase
F-A-S verbal fluency tests
breast cancer survivors
-
improvement was demonstrated
#3
Qigong
decrease
distress
breast cancer survivors
-
reported the most reduction
#4
mindfulness-based exercise
increase
self-report of cognitive function and distress
breast cancer survivors after treatment
-
may be superior to gentle exercise alone or survivorship support for improving
#5
Abstract

PURPOSE: The purpose of this pilot study was to evaluate the feasibility of an 8-week Qigong intervention to improve objectively and subjectively assessed cognitive function in breast cancer survivors who were 2 months to 8 years post completion of chemotherapy and radiation therapy. METHODS: A randomized, single-blind, three-arm intervention pilot was conducted to compare Qigong to gentle exercise and survivorship support. Feasibility was measured by recruitment, group session attendance, and adherence to home practice for the two exercise groups. Changes in self-report and objectively measured cognitive function were compared between the three groups from baseline (T1) to completion of the intervention (T2) and 4 weeks post intervention (T3). RESULTS: Fifty participants consented (83% of desired sample) with an overall attrition rate of 28%. Attrition was highest for the gentle exercise group (50%). Group attendance adherence ranged from 44 to 67%. The a priori established rate of 75% weekly attendance was not achieved, nor was the goal of 75% adherence to home practice for the two exercise groups (7 to 41%). Self-report of cognitive function improved most for the Qigong group (p = .01). Improvement was demonstrated for the Trail Making A (gentle exercise, p = .007) and F-A-S verbal fluency (support group, p = .02) tests. Qigong participants reported the most reduction of distress (p = .02). CONCLUSIONS: The study results suggest that mindfulness-based exercise may be superior to gentle exercise alone or survivorship support for improving self-report of cognitive function and distress after treatment for breast cancer. The mindfulness component may enhance the positive impact of exercise on cognitive function.

Medical Subject Headings (MeSH)
AdultAgedBreast NeoplasmsCancer SurvivorsCognitionCognition DisordersFemaleHumansMiddle AgedPilot ProjectsQigongQuality of LifeTreatment Outcome
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations52
Citations/Year8.7
Relative Citation Ratio3.28
NIH Percentile86.7%
Research Impact Scores
APT Score0.95
Weight Score2.43
Normalized Score0.66
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