The role of nutrition in ageing: A narrative review from the perspective of the European joint action on frailty - ADVANTAGE JA.
Study Goal
The researchers aimed to examine the role of nutrition, including the Mediterranean Diet, in aging, frailty risk, and potential interventions for frail or pre-frail patients.
Results Summary
The study found that promoting a Mediterranean Diet is beneficial for frail patients, alongside adequate protein intake and Vitamin D supplementation, as it helps mitigate frailty risks and consequences.
Population
Frail and pre-frail patients, particularly older adults at risk of malnutrition.
Effective Dosage
Not specified for Mediterranean Diet; protein intake recommended at 1-1.2 g per kg of body weight per day.
Duration
Not specified.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Mini Nutritional Assessment | no change | recognizing malnutrition and the risk of malnutrition | - | acceptable sensitivity/specificity | is a validated tool with acceptable sensitivity/specificity | #1 |
Vitamin D supplementation | decrease | risk of falls and fractures | Frail patients | - | needed | #2 |
Mediterranean diet | increase | - | - | - | promotion is beneficial | #3 |
protein intake | increase | - | - | at least 1-1.2 g per kilogram of body weight per day | is beneficial | #4 |
BACKGROUND AND PURPOSE: There is sufficient evidence that nutrition and frailty status are related. In order to deliver quality management of frail and pre-frail patients, clinicians and dieticians should understand the role of nutrition in the concept of frailty. This study examines the role of nutrition in ageing in general, malnutrition and the risk of frailty, individual nutritional factors as the risk factors of frailty and lastly nutritional interventions that have a significant role in frailty. METHODS: A literature search was conducted in the following databases: PubMed, Cochrane, Embase, Cinahl and UpToDate. The criterion in selecting the literature was that articles were published between 2002 and 2017. From 39,885 initial hits, 28 publications were selected. RESULTS: Malnutrition or being at risk of malnutrition increases the risk of frailty and its consequences. With regard to the importance of recognizing malnutrition and the risk of malnutrition, the Mini Nutritional Assessment is a validated tool with acceptable sensitivity/specificity to be used for screening and assessment. Frail patients who are at an elevated risk of falls and fractures need Vitamin D supplementation. The promotion of a Mediterranean diet and a protein intake of at least 1-1.2 g per kilogram of body weight per day is beneficial. CONCLUSIONS: One of the main variable risk factors for the development of frailty can be unsuitable nourishment and there is evidence that nutrition and frailty status are related. Successful comprehensive management of frailty requires a balanced healthy nutrition at all ages, preferably in combination with physical activity.