Anti-inflammatory effects of Melatonin: A mechanistic review.
Study Goal
The researchers aimed to assess the anti-inflammatory activity of melatonin, focusing on the mechanisms responsible for this behavior.
Results Summary
The study found that melatonin exhibits anti-inflammatory properties, which could be beneficial against chronic inflammation underlying many chronic diseases. The review highlights melatonin's role in immunomodulation, antioxidant defense, and its potential therapeutic effects.
Population
Not specified (general human population inferred)
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
melatonin | neutral | regulation of mood, sleep, reproduction, promotion of immunomodulation, antioxidant defense and as an anti-inflammatory agent | humans | - | participates in | #1 |
melatonin | decrease | chronic inflammation | - | - | could yield beneficial effects | #2 |
N-acetyl-5-methoxy-tryptamine (melatonin) is a natural substance produced both by plants, as a secondary metabolite, and animals, by the pineal gland and other tissues. In humans, melatonin participates in numerous functions including the regulation of mood, sleep, reproduction, promotion of immunomodulation, antioxidant defense and as an anti-inflammatory agent. The anti-inflammatory activity of melatonin could yield beneficial effects on intake, particularly against the chronic inflammation which underlies many chronic diseases. This review aims to provide an assessment of the literature data on the anti-inflammatory activity of melatonin, with a particular focus on the mechanisms responsible for this behavior. We can conclude that many