Implementation of Low Glycemic Index Diet Together with Cornstarch in Post-Gastric Bypass Hypoglycemia: Two Case Reports.
Study Goal
The researchers aimed to evaluate the efficacy of uncooked cornstarch, a low-glycemic index carbohydrate, in addition to a high-fiber diet, for treating post-bariatric hypoglycemia (PBH).
Results Summary
The study found that uncooked cornstarch, combined with a high-fiber diet, led to more stable glucose levels and a significant reduction in time spent in hypoglycemia in two patients with severe PBH. Continuous Glucose Monitoring (CGM) showed improved glycemic control after 12–16 weeks of intervention.
Population
Two young women with severe postprandial and fasting hypoglycemia following Roux-en-Y gastric bypass (RYGB).
Effective Dosage
1.25 g/kg body weight and 1.8 g/kg body weight.
Duration
12–16 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
uncooked cornstarch in addition to a high-fiber diet | no change | glucose levels throughout monitoring | two young women suffering from severe postprandial and fasting hypoglycemia following Roux-en-Y gastric bypass (RYGB) | - | showed more stable | #1 |
uncooked cornstarch in addition to a high-fiber diet | decrease | time spent in hypoglycemia | two young women suffering from severe postprandial and fasting hypoglycemia following Roux-en-Y gastric bypass (RYGB) | - | remarkable reduction | #2 |
Post-bariatric hypoglycemia (PBH) is an increasingly recognized long-term complication of bariatric surgery. The nutritional treatment of PBH includes a high-fiber diet and the restriction of soluble and high-glycemic index carbohydrates; however, these measures are not always enough to prevent hypoglycemia. We evaluated the efficacy of uncooked cornstarch, a low-glycemic index carbohydrate characterized by slow intestinal degradation and absorption, in addition to a high-fiber diet, for the treatment of PBH. We report the cases of two young women suffering from severe postprandial and fasting hypoglycemia following Roux-en-Y gastric bypass (RYGB). The patients underwent Continuous Glucose Monitoring (CGM) before and 12⁻16 weeks after the administration of uncooked cornstarch (respectively 1.25 g/kg b.w. and 1.8 g/kg b.w.) in addition to a high-fiber diet. In both patients, CGM showed more stable glucose levels throughout monitoring, a remarkable reduction of the time spent in hypoglycemia (.