The neuroprotective role of melatonin in neurological disorders.
Study Goal
The researchers aimed to review melatonin's neuroprotective role and its involvement in the pathophysiology of neurological disorders such as stroke, Alzheimer's disease, and Parkinson's disease.
Results Summary
The study found that melatonin has a wide-ranging regulatory and neuroprotective role, with potential therapeutic benefits for neurological disorders and no reported side effects. It also indicated disturbed melatonin levels in certain neurological conditions, suggesting its involvement in disease pathophysiology.
Population
Patients with neurological conditions (stroke, Alzheimer's disease, Parkinson's disease)
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
melatonin | neutral | regulatory and neuroprotective role | - | - | has a wide-ranging regulatory and neuroprotective role | #1 |
melatonin level | neutral | melatonin level | patients with stroke, Alzheimer's disease, and Parkinson's disease | - | disturbed | #2 |
melatonin | neutral | pathophysiology of stroke, Alzheimer's disease, and Parkinson's disease | - | - | involvement in the pathophysiology | #3 |
melatonin | neutral | neuroprotection | patients with neurological disorders | - | promising potential therapeutic neuroprotective agent | #4 |
melatonin | no change | side effects | - | - | no side effects | #5 |
Melatonin is a neurohormone secreted from the pineal gland and has a wide-ranging regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in some neurological conditions such as stroke, Alzheimer's disease, and Parkinson's disease, which indicates its involvement in the pathophysiology of these diseases. Its properties qualify it to be a promising potential therapeutic neuroprotective agent, with no side effects, for some neurological disorders. This review discusses and localizes the effect of melatonin in the pathophysiology of some diseases.