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Mindfulness and meditation: treating cognitive impairment and reducing stress in dementia.

Reviews in the neurosciences
January 1, 1970
Jesse Russell-Williams et al. (6 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to investigate how meditation, particularly mindfulness, can reduce stress and enhance cognition in individuals with Alzheimer's disease, dementia, mild cognitive impairment, or subjective cognitive decline.

Results Summary

The study found that mindfulness-based interventions led to significant improvements, including reduced cognitive decline, lower perceived stress, enhanced quality of life, and increased functional connectivity and cerebral blood flow in brain regions. Three randomized controlled trials supported these findings, though measures varied across studies.

Population

Individuals with Alzheimer's disease, dementia, mild cognitive impairment, or subjective cognitive decline.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (21)
InterventionDirectionEndpointPopulationDosageImpactClaim #
meditation
decrease
stress
people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline
-
reduce
#1
meditation
increase
cognition
people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline
-
enhance
#2
meditation
decrease
dementia symptoms
people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline
-
ameliorates
#3
mindfulness-based stress reduction
decrease
cognitive decline
people with dementia or dementia-related memory conditions
-
reduction
#4
mindfulness-based stress reduction
decrease
perceived stress
people with dementia or dementia-related memory conditions
-
reduction
#5
mindfulness-based stress reduction
increase
quality of life
people with dementia or dementia-related memory conditions
-
increase
#6
mindfulness-based stress reduction
increase
functional connectivity
people with dementia or dementia-related memory conditions
-
increases
#7
mindfulness-based stress reduction
increase
percent volume brain change
people with dementia or dementia-related memory conditions
-
increases
#8
mindfulness-based stress reduction
increase
cerebral blood flow in areas of the cortex
people with dementia or dementia-related memory conditions
-
increases
#9
Kirtan Kriya meditation
decrease
cognitive decline
people with dementia or dementia-related memory conditions
-
reduction
#10
Kirtan Kriya meditation
decrease
perceived stress
people with dementia or dementia-related memory conditions
-
reduction
#11
Kirtan Kriya meditation
increase
quality of life
people with dementia or dementia-related memory conditions
-
increase
#12
Kirtan Kriya meditation
increase
functional connectivity
people with dementia or dementia-related memory conditions
-
increases
#13
Kirtan Kriya meditation
increase
percent volume brain change
people with dementia or dementia-related memory conditions
-
increases
#14
Kirtan Kriya meditation
increase
cerebral blood flow in areas of the cortex
people with dementia or dementia-related memory conditions
-
increases
#15
mindfulness-based Alzheimer's stimulation
decrease
cognitive decline
people with dementia or dementia-related memory conditions
-
reduction
#16
mindfulness-based Alzheimer's stimulation
decrease
perceived stress
people with dementia or dementia-related memory conditions
-
reduction
#17
mindfulness-based Alzheimer's stimulation
increase
quality of life
people with dementia or dementia-related memory conditions
-
increase
#18
mindfulness-based Alzheimer's stimulation
increase
functional connectivity
people with dementia or dementia-related memory conditions
-
increases
#19
mindfulness-based Alzheimer's stimulation
increase
percent volume brain change
people with dementia or dementia-related memory conditions
-
increases
#20
mindfulness-based Alzheimer's stimulation
increase
cerebral blood flow in areas of the cortex
people with dementia or dementia-related memory conditions
-
increases
#21
Abstract

This study investigates the relationship between mindfulness, meditation, cognition and stress in people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline. Accordingly, we explore how the use of meditation as a behavioural intervention can reduce stress and enhance cognition, which in turn ameliorates some dementia symptoms. A narrative review of the literature was conducted with any studies using meditation as an intervention for dementia or dementia-related memory conditions meeting inclusion criteria. Studies where moving meditation was the main intervention were excluded due to the possible confounding of exercise. Ten papers were identified and reviewed. There was a broad use of measures across all studies, with cognitive assessment, quality of life and perceived stress being the most common. Three studies used functional magnetic resonance imaging to measure functional changes to brain regions during meditation. The interventions fell into the following three categories: mindfulness, most commonly mindfulness-based stress reduction (six studies); Kirtan Kriya meditation (three studies); and mindfulness-based Alzheimer's stimulation (one study). Three of these studies were randomised controlled trials. All studies reported significant findings or trends towards significance in a broad range of measures, including a reduction of cognitive decline, reduction in perceived stress, increase in quality of life, as well as increases in functional connectivity, percent volume brain change and cerebral blood flow in areas of the cortex. Limitations and directions for future studies on meditation-based treatment for AD and stress management are suggested.

Medical Subject Headings (MeSH)
Cognition DisordersDementiaHumansMindfulnessNegotiatingStress, Psychological
Study Links
Quality Scores
SafetyNot Assessed
Efficacy80/10
Quality75/10
Citation Metrics
Total Citations47
Citations/Year6.7
Relative Citation Ratio2.81
NIH Percentile83.6%
Research Impact Scores
APT Score0.75
Weight Score1.78
Normalized Score0.67
Related Supplements
Mindfulness and meditation: treating cognitive impairment an... | Panacea Index