Mindfulness and meditation: treating cognitive impairment and reducing stress in dementia.
Study Goal
The researchers aimed to investigate how meditation, particularly mindfulness, can reduce stress and enhance cognition in individuals with Alzheimer's disease, dementia, mild cognitive impairment, or subjective cognitive decline.
Results Summary
The study found that mindfulness-based interventions led to significant improvements, including reduced cognitive decline, lower perceived stress, enhanced quality of life, and increased functional connectivity and cerebral blood flow in brain regions. Three randomized controlled trials supported these findings, though measures varied across studies.
Population
Individuals with Alzheimer's disease, dementia, mild cognitive impairment, or subjective cognitive decline.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
meditation | decrease | stress | people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline | - | reduce | #1 |
meditation | increase | cognition | people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline | - | enhance | #2 |
meditation | decrease | dementia symptoms | people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline | - | ameliorates | #3 |
mindfulness-based stress reduction | decrease | cognitive decline | people with dementia or dementia-related memory conditions | - | reduction | #4 |
mindfulness-based stress reduction | decrease | perceived stress | people with dementia or dementia-related memory conditions | - | reduction | #5 |
mindfulness-based stress reduction | increase | quality of life | people with dementia or dementia-related memory conditions | - | increase | #6 |
mindfulness-based stress reduction | increase | functional connectivity | people with dementia or dementia-related memory conditions | - | increases | #7 |
mindfulness-based stress reduction | increase | percent volume brain change | people with dementia or dementia-related memory conditions | - | increases | #8 |
mindfulness-based stress reduction | increase | cerebral blood flow in areas of the cortex | people with dementia or dementia-related memory conditions | - | increases | #9 |
Kirtan Kriya meditation | decrease | cognitive decline | people with dementia or dementia-related memory conditions | - | reduction | #10 |
Kirtan Kriya meditation | decrease | perceived stress | people with dementia or dementia-related memory conditions | - | reduction | #11 |
Kirtan Kriya meditation | increase | quality of life | people with dementia or dementia-related memory conditions | - | increase | #12 |
Kirtan Kriya meditation | increase | functional connectivity | people with dementia or dementia-related memory conditions | - | increases | #13 |
Kirtan Kriya meditation | increase | percent volume brain change | people with dementia or dementia-related memory conditions | - | increases | #14 |
Kirtan Kriya meditation | increase | cerebral blood flow in areas of the cortex | people with dementia or dementia-related memory conditions | - | increases | #15 |
mindfulness-based Alzheimer's stimulation | decrease | cognitive decline | people with dementia or dementia-related memory conditions | - | reduction | #16 |
mindfulness-based Alzheimer's stimulation | decrease | perceived stress | people with dementia or dementia-related memory conditions | - | reduction | #17 |
mindfulness-based Alzheimer's stimulation | increase | quality of life | people with dementia or dementia-related memory conditions | - | increase | #18 |
mindfulness-based Alzheimer's stimulation | increase | functional connectivity | people with dementia or dementia-related memory conditions | - | increases | #19 |
mindfulness-based Alzheimer's stimulation | increase | percent volume brain change | people with dementia or dementia-related memory conditions | - | increases | #20 |
mindfulness-based Alzheimer's stimulation | increase | cerebral blood flow in areas of the cortex | people with dementia or dementia-related memory conditions | - | increases | #21 |
This study investigates the relationship between mindfulness, meditation, cognition and stress in people with Alzheimer's disease (AD), dementia, mild cognitive impairment and subjective cognitive decline. Accordingly, we explore how the use of meditation as a behavioural intervention can reduce stress and enhance cognition, which in turn ameliorates some dementia symptoms. A narrative review of the literature was conducted with any studies using meditation as an intervention for dementia or dementia-related memory conditions meeting inclusion criteria. Studies where moving meditation was the main intervention were excluded due to the possible confounding of exercise. Ten papers were identified and reviewed. There was a broad use of measures across all studies, with cognitive assessment, quality of life and perceived stress being the most common. Three studies used functional magnetic resonance imaging to measure functional changes to brain regions during meditation. The interventions fell into the following three categories: mindfulness, most commonly mindfulness-based stress reduction (six studies); Kirtan Kriya meditation (three studies); and mindfulness-based Alzheimer's stimulation (one study). Three of these studies were randomised controlled trials. All studies reported significant findings or trends towards significance in a broad range of measures, including a reduction of cognitive decline, reduction in perceived stress, increase in quality of life, as well as increases in functional connectivity, percent volume brain change and cerebral blood flow in areas of the cortex. Limitations and directions for future studies on meditation-based treatment for AD and stress management are suggested.