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Melatonin-mediated inhibition of Cav3.2 T-type Ca

Journal of pineal research
May 1, 2018
Yuan Zhang et al. (9 authors)
Journal ArticleMolecular Study
Extracted Claims (2)
InterventionDirectionEndpointPopulationDosageImpactClaim #
melatonin
increase
antinociceptive activity of sensory neurons
sensory neurons
-
implicate in the antinociceptive activity
#1
melatonin
increase
Cav3.2 T-type Ca
-
-
identify a critical role in functionally regulating
#2
Abstract

Recent studies implicate melatonin in the antinociceptive activity of sensory neurons. However, the underlying mechanisms are still largely unknown. Here, we identify a critical role of melatonin in functionally regulating Cav3.2 T-type Ca

Medical Subject Headings (MeSH)
AnimalsCalcium Channels, T-TypeHyperalgesiaMelatoninMembrane PotentialsMice, Inbred ICRProtein Kinase CReceptor, Melatonin, MT2Sensory Receptor CellsSignal TransductionTrigeminal Ganglion
Study Links
PubMed ID29437250
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Melatonin-mediated inhibition of Cav3.2 T-type Ca | Panacea Index