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High protein consumption in trained women: bad to the bone?

Journal of the International Society of Sports Nutrition
January 1, 2018
Jose Antonio et al. (5 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether a high-protein diet affects whole body and lumbar bone mineral content in exercise-trained women.

Results Summary

The study found no significant differences in whole body bone mineral density, lumbar bone mineral density, T-scores, lean body mass, or fat mass between the high-protein and control groups, despite an 87% higher protein intake in the high-protein group.

Population

Exercise-trained women

Effective Dosage

Control: 1.5±0.3 g/kg/d; High-protein: 2.8±1.1 g/kg/d

Duration

6 months

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
high-protein diet
no change
whole body bone mineral density
exercise-trained women
-
had no effect
#1
high-protein diet
no change
lumbar bone mineral density
exercise-trained women
-
had no effect
#2
high-protein diet
no change
T-scores
exercise-trained women
-
had no effect
#3
high-protein diet
no change
lean body mass
exercise-trained women
-
had no effect
#4
high-protein diet
no change
fat mass
exercise-trained women
-
had no effect
#5
high-protein diet
increase
protein intake
exercise-trained women
87%
higher protein intake
#6
Abstract

BACKGROUND: It has been posited that the consumption of extra protein (> 0.8 g/kg/d) may be deleterious to bone mineral content. However, there is no direct evidence to show that consuming a high-protein diet results in a demineralization of the skeleton. Thus, the primary endpoint of this randomized controlled trial was to determine if a high-protein diet affected various parameters of whole body and lumbar bone mineral content in exercise-trained women. METHODS: Twenty-four women volunteered for this 6-month investigation ( RESULTS: During the 6-month treatment period, there was a significant difference in protein intake between the control and high-protein groups (mean±SD; control: 1.5±0.3, high-protein: 2.8±1.1 g/kg/d); however, there were no differences in the consumption total calories, carbohydrate or fat. Whole body bone mineral density did not change in the control (pre: 1.22±0.08, post: 1.22±0.09 g/cm CONCLUSION: Despite an 87% higher protein intake (high-protein versus control), 6 months of a high-protein diet had no effect on whole body bone mineral density, lumbar bone mineral density, T-scores, lean body mass or fat mass.

Medical Subject Headings (MeSH)
Absorptiometry, PhotonAdultAthletesBody CompositionBone DensityDiet, High-ProteinDietary ProteinsExerciseFemaleHumansSports Nutritional Physiological Phenomena
Study Links
Quality Scores
Safety85
Efficacy70/10
Quality80/10
Citation Metrics
Total Citations14
Citations/Year2.0
Relative Citation Ratio0.98
NIH Percentile49.3%
Research Impact Scores
APT Score0.50
Weight Score2.07
Normalized Score0.78
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