Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women.
Study Goal
The researchers aimed to evaluate the efficacy of green coffee bean extract combined with an energy-restricted diet on body composition and serum adipocytokines in obese women.
Results Summary
The study found that green coffee bean extract combined with an energy-restricted diet led to significant reductions in body weight, fat mass indices, and waist-to-hip ratio, along with improved lipid metabolism and increased adiponectin levels in obese women. The intervention group showed greater improvements compared to the placebo group.
Population
Obese women aged 20-45 years.
Effective Dosage
400 mg green coffee bean extract daily.
Duration
8 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
green coffee bean extract combined with an energy-restricted diet | decrease | body weight | obese women | - | significant reductions | #1 |
green coffee bean extract combined with an energy-restricted diet | decrease | body mass index | obese women | - | significant reductions | #2 |
green coffee bean extract combined with an energy-restricted diet | decrease | fat mass index | obese women | - | significant reductions | #3 |
green coffee bean extract combined with an energy-restricted diet | decrease | waist-to-hip circumference ratio | obese women | - | significant reductions | #4 |
green coffee bean extract | decrease | serum total cholesterol | obese women | - | significantly decreased | #5 |
green coffee bean extract | decrease | low-density lipoprotein | obese women | - | significantly decreased | #6 |
green coffee bean extract | decrease | leptin | obese women | - | significantly decreased | #7 |
green coffee bean extract | decrease | plasma free fatty acids | obese women | - | significantly decreased | #8 |
green coffee bean extract | increase | serum adiponectin concentration | obese women | - | significantly increased | #9 |
green coffee bean extract combined with an energy-restricted diet | neutral | fat accumulation | obese people | - | affects | #10 |
green coffee bean extract combined with an energy-restricted diet | neutral | lipid metabolism | obese people | - | affects | #11 |
BACKGROUND AND OBJECTIVES: Obesity has become a public health problem and is a cause of some preventable illnesses. Among several methods for treating obesity, the use of food supplements is highly common. A commonly used food supplement is green coffee bean extract. The objective of this study was to evaluate the efficacy of green coffee bean extract combined with an energy-restricted diet on the body composition and serum adipocytokines in obese women. METHODS AND STUDY DESIGN: In this randomised clinical trial, 64 obese women aged 20-45 years were selected and divided into two groups: an intervention group (receiving 400 mg green coffee bean extract for 8 weeks) and control group (receiving placebo). All participants were on an energy-restricted diet. The body composition, leptin, adiponectin, lipid profile, free fatty acids (FFAs), and fasting blood sugar were compared between the two groups. RESULTS: We observed significant reductions in the body weight, body mass and fat mass indices, and waist-to-hip circumference ratio in both groups; however, the decrease was higher in the intervention group. Moreover, serum total cholesterol, low-density lipoprotein, leptin, and plasma free fatty acids significantly decreased in the intervention group (p<0.05) after adjustment for energy and fibre intake. The serum adiponectin concentration significantly increased in the intervention group (p<0.05). CONCLUSIONS: Green coffee bean extract combined with an energy-restricted diet affects fat accumulation and lipid metabolism and is thus an inexpensive method for weight control in obese people.