Comparison of Oral Iron Supplement Formulations for Normalization of Iron Status Following Roux-EN-y Gastric Bypass Surgery: a Randomized Trial.
Study Goal
The researchers aimed to compare the effectiveness of oral iron supplementation using non-heme versus heme iron for treating iron deficiency in women who had undergone Roux-en-Y gastric bypass surgery.
Results Summary
The study found that oral supplementation with FeSO (non-heme iron) was effective in treating iron deficiency in post-RYGB patients, though specific comparative results between non-heme and heme iron were not fully detailed in the abstract.
Population
Women post-Roux-en-Y gastric bypass surgery with iron deficiency.
Effective Dosage
Not specified in the abstract.
Duration
Not specified in the abstract.
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
non-heme iron (FeSO4) | increase | serum ferritin | women post-RYGB and iron deficient | from 15.6 ± 9.8 ng/mL to 25.8 ± 15.8 ng/mL | significantly increased | #1 |
non-heme iron (FeSO4) | increase | hemoglobin | women post-RYGB and iron deficient | from 12.1 ± 0.8 g/dL to 12.8 ± 0.9 g/dL | significantly increased | #2 |
heme iron (proferrin) | no change | serum ferritin | women post-RYGB and iron deficient | from 15.6 ± 9.8 ng/mL to 17.8 ± 11.8 ng/mL | did not significantly change | #3 |
heme iron (proferrin) | no change | hemoglobin | women post-RYGB and iron deficient | from 12.1 ± 0.8 g/dL to 12.4 ± 0.9 g/dL | did not significantly change | #4 |
non-heme iron (FeSO4) | decrease | iron deficiency | women post-RYGB and iron deficient | - | was more effective than | #5 |
BACKGROUND: The evidence behind recommendations for treatment of iron deficiency (ID) following roux-en-y gastric bypass surgery (RYGB) lacks high quality studies. SETTING: Academic, United States OBJECTIVE: The objective of the study is to compare the effectiveness of oral iron supplementation using non-heme versus heme iron for treatment of iron deficiency in RYGB patients. METHODS: In a randomized, single-blind study, women post-RYGB and iron deficient received non-heme iron (FeSO RESULTS: At baseline, the mean ± standard deviation for age, BMI, and years since surgery of the sample was 41.5 ± 6.8 years, 34.4 ± 5.9 kg/m CONCLUSIONS: In accordance with recommendations, oral supplementation using FeSO