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Current and Emerging Strategies in Osteoporosis Management.

Current pharmaceutical design
January 1, 2017
Stefka Ivanova et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review established and emerging trends in the prevention and treatment of bone loss, including the role of calcium in osteoporosis management.

Results Summary

The study highlights that a diet rich in calcium and vitamin D, along with healthy lifestyle and exercise, is part of non-pharmacological treatment strategies for osteoporosis. It suggests combining non-pharmacological and pharmacological approaches to minimize fracture risk.

Population

General population, with higher prevalence in postmenopausal women.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Herbal supplementation
neutral
prevention and management of osteoporosis
-
-
suggested as addition to the well-established therapy
#1
physical exercises
neutral
prevention and management of osteoporosis
-
-
suggested as addition to the well-established therapy
#2
diet rich of calcium and vitamin D
neutral
prevention and treatment of bone loss
-
-
include
#3
healthy lifestyle
neutral
prevention and treatment of bone loss
-
-
include
#4
proper exercise plan
neutral
prevention and treatment of bone loss
-
-
include
#5
combination of non-pharmacological and pharmacological approaches
decrease
minimization of the fracture risk
osteoporosis
-
have to consider
#6
Abstract

The abnormal loss of bone tissue is defined as osteoporosis. Increased risk of fractures, low bone mineral density (BMD) and loss of the structural and biomechanical properties of the bone tissue characterize this pathological condition. Physiologically bone undergoes a continuous remodeling process involving balance between the activity of osteoblast and osteoclast. Disruption in this balanced condition increases the risk of osteoporosis. Both sexes are affected, but with higher prevalence in women after menopause. This review aims to enlighten the established and emerging trends in prevention and treatment of bone loss. Herbal supplementation and physical exercises are suggested as addition to the well-established therapy in prevention and management of osteoporosis. Treatment strategies of osteoporosis include non- pharmacological treatment - diet rich of calcium and vitamin D, healthy lifestyle, proper exercise plan, and pharmacological therapy. Preventive and treatment strategies have to consider combination of non-pharmacological and pharmacological approaches for minimization of the fracture risk in osteoporosis.

Medical Subject Headings (MeSH)
AnimalsBone DensityBone Density Conservation AgentsBone ResorptionCalciumExerciseHumansOsteoporosisRisk FactorsVitamin D
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality65/10
Citation Metrics
Total Citations6
Citations/Year0.8
Relative Citation Ratio0.24
NIH Percentile12.2%
Research Impact Scores
APT Score0.05
Weight Score0.81
Normalized Score0.63
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