Mindfulness-Based Stress Reduction in Women with Overweight or Obesity: A Randomized Clinical Trial.
Study Goal
To evaluate the feasibility and cardiometabolic effects of mindfulness-based stress reduction (MBSR) in women with overweight or obesity.
Results Summary
MBSR significantly improved mindfulness and reduced perceived stress, with beneficial effects on fasting glucose, but no significant changes in blood pressure, weight, or insulin resistance.
Population
Women with BMI ≥ 25 kg/m² (overweight or obese).
Effective Dosage
Not specified
Duration
16 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindfulness-based stress reduction (MBSR) | increase | mindfulness | women with overweight or obesity | mean change from baseline, 4.5 vs. -1.0 | significantly improved | #1 |
mindfulness-based stress reduction (MBSR) | decrease | perceived stress | women with overweight or obesity | -3.6 vs. -1.3 | significantly decreased | #2 |
mindfulness-based stress reduction (MBSR) | decrease | fasting glucose | women with overweight or obesity | -8.9 mg/dL | significant reductions | #3 |
mindfulness-based stress reduction (MBSR) | decrease | fasting glucose | women with overweight or obesity | -9.3 mg/dL | significant reductions | #4 |
health education | no change | fasting glucose | women with overweight or obesity | - | did not significantly improve | #5 |
mindfulness-based stress reduction (MBSR) | no change | blood pressure | women with overweight or obesity | - | no significant changes | #6 |
mindfulness-based stress reduction (MBSR) | no change | weight | women with overweight or obesity | - | no significant changes | #7 |
mindfulness-based stress reduction (MBSR) | no change | insulin resistance | women with overweight or obesity | - | no significant changes | #8 |
OBJECTIVE: To evaluate the feasibility and cardiometabolic effects of mindfulness-based stress reduction (MBSR) in women with overweight or obesity. METHODS: Eighty-six women with BMI ≥ 25 kg/m RESULTS: Compared to health education, the MBSR group demonstrated significantly improved mindfulness at 8 weeks (mean change from baseline, 4.5 vs. -1.0; P = 0.03) and significantly decreased perceived stress at 16 weeks (-3.6 vs. -1.3, P = 0.01). In the MBSR group, there were significant reductions in fasting glucose at 8 weeks (-8.9 mg/dL, P = 0.02) and at 16 weeks (-9.3 mg/dL, P = 0.02) compared to baseline. Fasting glucose did not significantly improve in the health education group. There were no significant changes in blood pressure, weight, or insulin resistance in the MBSR group. CONCLUSIONS: In women with overweight or obesity, MBSR significantly reduces stress and may have beneficial effects on glucose. Future studies demonstrating long-term cardiometabolic benefits of MBSR will be key for establishing MBSR as an effective tool in the management of obesity.