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Consumption of a 5-mg Melatonin Supplement Does Not Affect 32.2-km Cycling Time Trial Performance.

Journal of strength and conditioning research
October 1, 2018
Kyle J Brandenberger et al. (4 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether a 5-mg melatonin supplement affects performance in a 32.2-km cycling time trial in a thermoneutral environment.

Results Summary

The study found no significant difference in time trial completion, power output, or rectal temperature between melatonin and placebo trials, suggesting melatonin does not impact cycling performance under these conditions.

Population

Trained male cyclists (n=10; age 25.1 ± 4.0 years; VO2max 62.7 ± 6.3 ml·kg·min).

Effective Dosage

5 mg, administered once 15 minutes before exercise.

Duration

Single-dose intervention.

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
5-mg melatonin supplement
no change
32.2-km cycling time trial performance
trained male subjects
-
does not affect
#1
5-mg melatonin supplement
no change
mean 32.2-km time trial completion times
trained male subjects
-
were not different
#2
5-mg melatonin supplement
no change
mean time trial power output
trained male subjects
-
was not different
#3
5-mg melatonin supplement
no change
rectal temperature
trained male subjects
-
was not significantly different
#4
Abstract

Brandenberger, KJ, Ingalls, CP, Rupp, JC, and Doyle, JA. Consumption of a 5-mg melatonin supplement does not affect 32.2-km cycling time trial performance. J Strength Cond Res 32(10): 2872-2877, 2018-Some studies suggest that exogenous melatonin supplementation may improve athletic performance in hot humid environments because of its precooling effect. However, melatonin is also consumed as a sleep aid for its depressive effects on the central nervous system (CNS), which may hinder performance. Therefore, this study was conducted to determine whether consuming a 5-mg supplement of melatonin would affect performance in a laboratory-simulated 32.2-km cycling time trial. The time trial was conducted in a thermoneutral environment to separate CNS depressive effects of the melatonin from the cooling effects. Trained male subjects (n = 10; V[Combining Dot Above]O2max = 62.7 ± 6.3 ml·kg·min; age = 25.1 ± 4.0 years; mass = 69.9 ± 9.1 kg; height = 176.0 ± 7.1 cm) performed three 32.2-km time trials on an electronically braked cycle ergometer. The first trial was a familiarization. During the 2 experimental trials, subjects received in a random order either a placebo or a 5-mg melatonin supplement 15 minutes before exercise in a double-blind, crossover design. Variables were measured before exercise and at 8-km intervals. The mean 32.2-km time trial completion times for the melatonin (64.94 ± 5.95 minutes) and placebo (65.26 ± 6.85 minutes) trials were not different (p = 0.682). The mean time trial power output for the melatonin (190.4 ± 40.4 watts) and placebo (190.0 ± 45.7 watts) trials was not different (p = 0.927). Rectal temperature was not significantly different for melatonin compared with placebo (p = 0.827). These results suggest that a 5-mg melatonin supplement administered 15 minutes before exercise does not measurably impact the performance of a 32.2-km cycling time trial in a thermoneutral environment.

Medical Subject Headings (MeSH)
AdultAthletic PerformanceBicyclingCross-Over StudiesDietary SupplementsDouble-Blind MethodExercise TestHeart RateHumansMaleMelatoninYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy10/10
Quality85/10
Citation Metrics
Total Citations11
Citations/Year1.6
Relative Citation Ratio0.76
NIH Percentile40.1%
Research Impact Scores
APT Score0.25
Weight Score2.11
Normalized Score0.41
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