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The effect of 8-week different-intensity walking exercises on serum hepcidin, IL-6, and iron metabolism in pre-menopausal women.

Physiology international
January 1, 1970
G Buyukyazi et al. (8 authors)
Comparative StudyJournal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to examine the chronic effects of two different-intensity walking exercises on hepcidin, interleukin 6 (IL-6), and markers of iron metabolism in premenopausal women.

Results Summary

The study compared moderate tempo walking and brisk walking over 8 weeks, finding that both exercise groups showed changes in hepcidin and iron metabolism markers, though specific outcomes were not detailed in the abstract.

Population

Premenopausal women

Effective Dosage

3 days/week, starting from 30 to 51 minutes per session (moderate tempo walking at ~50-55% HRR, brisk walking at ~70-75% HRR)

Duration

8 weeks

Interactions

None mentioned

Extracted Claims (2)
InterventionDirectionEndpointPopulationDosageImpactClaim #
moderate tempo walking group (MTWG)
neutral
hepcidin, interleukin 6 (IL-6), and markers of iron metabolism
pre-menopausal women
-
chronic effects of
#1
brisk walking group (BWG)
neutral
hepcidin, interleukin 6 (IL-6), and markers of iron metabolism
pre-menopausal women
-
chronic effects of
#2
Abstract

Objective Hepcidin may be an important mediator in exercise-induced iron deficiency. Despite the studies investigating acute exercise effects on hepcidin and markers of iron metabolism, we found no studies examining the chronic effects of walking exercises (WE) on hepcidin and markers of iron metabolism in premenopausal women. The chronic effects of two 8-week different-intensity WE on hepcidin, interleukin 6 (IL-6), and markers of iron metabolism in pre-menopausal women were examined. Methods Exercise groups (EG) [moderate tempo walking group (MTWG), n = 11; brisk walking group (BWG), n = 11] walked 3 days/week, starting from 30 to 51 min. Control group (CG; n = 8) did not perform any exercises. BWG walked at ∼70%-75%; MTWG at ∼50%-55% of HRR

Medical Subject Headings (MeSH)
AdultBiomarkersExerciseFemaleHepcidinsHumansInflammation MediatorsInterleukin-6IronMiddle AgedOxygen ConsumptionPremenopauseTime FactorsWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality70/10
Citation Metrics
Total Citations6
Citations/Year0.8
Relative Citation Ratio0.27
NIH Percentile13.8%
Research Impact Scores
APT Score0.25
Weight Score1.47
Normalized Score0.60
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