Prevalence and factors promoting the occurrence of vitamin D deficiency in the elderly.
Study Goal
The researchers aimed to summarize current knowledge about risk factors for vitamin D deficiency in the elderly, including the role of dietary factors like small sea fish consumption.
Results Summary
The study found that reduced consumption of small sea fish contributes to vitamin D deficiency in elderly populations, particularly in moderate climate countries, and highlighted sociodemographic and health factors exacerbating deficiency.
Population
Elderly individuals, especially women, living in moderate climate countries.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
reduced amount of vitamin D in the diet (small sea fish consumption) | increase | vitamin D deficiency | elderly people, especially women, who live in moderate climate countries | - | affects | #1 |
reduced content of 7-dehydrocholesterol | decrease | skin synthesis | elderly people, especially women, who live in moderate climate countries | - | causes decreased | #2 |
winter and spring | decrease | 25(OH)D3 | - | - | lowest seasonal concentration | #3 |
sun exposure | increase | 25(OH)D3 concentration | men | - | influences more strongly | #4 |
poor environmental conditions | increase | vitamin D deficiency | the elderly | - | increase the risk | #5 |
low economic status | increase | vitamin D deficiency | the elderly | - | increase the risk | #6 |
lower educational level | increase | vitamin D deficiency | the elderly | - | increase the risk | #7 |
drug exposure (smoking) | increase | vitamin D deficiency | the elderly | - | increase the risk | #8 |
reduced physical activity | increase | vitamin D deficiency | the elderly | - | increase the risk | #9 |
overall poor health | increase | vitamin D deficiency | the elderly | - | increase the risk | #10 |
obesity | decrease | skin exposure to sunlight | the elderly | - | causes reduced | #11 |
medications or supplements that contain vitamin D | decrease | deficiency | - | - | prevent | #12 |
staying in a nursing home that employ such supplementation | decrease | deficiency | - | - | prevent | #13 |
significant prevalence of diseases of the gastrointestinal tract | increase | cholecalciferol and ergocalciferol malabsorption | - | - | may contribute to | #14 |
significant prevalence of diseases of the gastrointestinal tract | decrease | their liver transformation | - | - | impair | #15 |
high incidence of chronic kidney disease in old age | decrease | processing hydroxylation of vitamin D | - | - | reduces | #16 |
high incidence of chronic kidney disease in old age | decrease | formation of active metabolites | - | - | reduces | #17 |
vitamin D deficiency | increase | bone mineralization disorders | - | - | can cause | #18 |
vitamin D deficiency | increase | cardiovascular diseases | - | - | increase incidence | #19 |
vitamin D deficiency | increase | cancers | - | - | increase incidence | #20 |
vitamin D deficiency | increase | type 2 diabetes | - | - | increase incidence | #21 |
vitamin D deficiency | increase | depression | - | - | increase incidence | #22 |
Vitamin D deficiency affects a large part of the population of elderly people, especially women, who live in moderate climate countries due to a reduced amount of vitamin D in the diet (small sea fish consumption) and reduced content of 7-dehydrocholesterol, which causes decreased skin synthesis. The lowest seasonal concentration of 25(OH)D3 is usually observed during winter and spring. Sun exposure influences 25(OH)D3 concentration more strongly in men than in women. Sociodemographic factors that increase the risk of vitamin D deficiency in the elderly include poor environmental conditions, low economic status, lower educational level, drug exposure (smoking), reduced physical activity, overall poor health and obesity, which causes reduced skin exposure to sunlight. The use of medications or supplements that contain vitamin D and staying in a nursing home that employ such supplementation are factors that prevent deficiency. Significant prevalence of diseases of the gastrointestinal tract may contribute to cholecalciferol and ergocalciferol malabsorption or impair their liver transformation. In addition, the high incidence of chronic kidney disease in old age reduces processing hydroxylation of vitamin D and the formation of active metabolites. Vitamin D deficiency can not only cause bone mineralization disorders, but also increase incidence of cardiovascular diseases, cancers, type 2 diabetes and depression. The aim of this study was to summarize current knowledge about the risk factors of vitamin D deficiency development in the elderly population.