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Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women.

Biogerontology
August 1, 2017
A Gmiat et al. (12 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether vitamin D modifies adaptation to exercise and reduces inflammation in elderly women.

Results Summary

The study hypothesized that vitamin D's anti-inflammatory properties would enhance exercise adaptation and reduce inflammation in elderly women, but specific results regarding Walking were not detailed in the abstract.

Population

Twenty-seven elderly women aged 67 ± 8 years.

Effective Dosage

Not specified in the abstract.

Duration

Not specified in the abstract.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Physical activity
decrease
inflammation
-
-
induces an anti-inflammatory effect
#1
vitamin D
decrease
inflammation
-
-
has also anti-inflammatory activity
#2
vitamin D
neutral
adaptation to exercise
elderly women
-
will modify adaptation to exercise
#3
vitamin D
decrease
inflammation
elderly women
-
reduce inflammation
#4
Abstract

Mechanisms underpinning age-related decreases in muscle strength and muscle mass relate to chronic inflammation. Physical activity induces an anti-inflammatory effect, but it is modulated by additional factors. We hypothesized that vitamin D, which has also anti-inflammatory activity will modify adaptation to exercise and reduce inflammation in elderly women. Twenty-seven women aged 67 ± 8 years were included and divided into groups with baseline vitamin D concentration more than 20 ng mL

Medical Subject Headings (MeSH)
Age FactorsAgedAgingCholecalciferolDietary SupplementsExercise TherapyFemaleHMGB1 ProteinHealthy AgingHumansInflammation MediatorsInterleukin-6LeucineMiddle AgedMuscle StrengthPolandPostural BalanceSex FactorsTime FactorsTreatment OutcomeWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality70/10
Citation Metrics
Total Citations35
Citations/Year4.4
Relative Citation Ratio1.79
NIH Percentile71.2%
Research Impact Scores
APT Score0.75
Weight Score1.91
Normalized Score0.60
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Changes in pro-inflammatory markers and leucine concentratio... | Panacea Index