Risk factors for recurrence after successful treatment of warts: the role of smoking habits.
Study Goal
The researchers aimed to determine the importance of individual characteristics and different therapy modalities, including Cryotherapy, in the recurrence of plantar warts.
Results Summary
The abstract does not provide specific results for Cryotherapy, focusing instead on pulsed dye laser (PDL) and CO₂ laser treatments. PDL showed the lowest recurrence rate, while smoking increased relapse risk.
Population
199 patients affected by multiple plantar warts.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
pulsed dye laser | decrease | recurrence | patients affected by multiple plantar warts | lowest rate | characterized by the lowest rate of recurrence | #1 |
CO2 laser | increase | risk of recurrence | patients affected by multiple plantar warts | - | risk of recurrence was increased | #2 |
smoking | increase | risk of warts relapse | smokers | 5-fold higher | risk of warts relapse is 5-fold higher | #3 |
BACKGROUND: Several therapies have been proposed for cutaneous warts without results concerning factors affecting recurrences. OBJECTIVE: To determine the importance of individual characteristics and different therapy modalities in the occurrence of relapses. METHODS: Observational prospective cohort study including 199 patients affected by multiple plantar warts treated as follows: 49 with keratolytics, 50 with CO RESULTS: Of patients, 57.8% showed a persistent clearance of warts after treatment with a higher recurrence-free interval when treated with PDL. Accordingly, the risk of recurrence was increased with CO CONCLUSIONS: Pulsed dye laser is characterized by the lowest rate of recurrence. Furthermore, our study highlights that the risk of warts relapse is 5-fold higher in smokers compared to non-smokers, revealing the importance of the effects of smoking on inflammation and immune response.