Panacea Index Logo

Command Palette

Search for a command to run...

Effects of a Short-Term High-Nitrate Diet on Exercise Performance.

Nutrients
January 1, 1970
Simone Porcelli et al. (9 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to assess whether a high-nitrate diet increases nitric oxide bioavailability and improves exercise performance compared to a control diet.

Results Summary

The high-nitrate diet significantly increased plasma nitrate and nitrite concentrations, reduced oxygen consumption during moderate exercise, increased muscle work during fatiguing exercise, and improved performance in a Repeated Sprint Ability test.

Population

Seven healthy male subjects

Effective Dosage

~8.2 mmol∙day(-1) (high-nitrate diet) vs. ~2.9 mmol∙day(-1) (control diet)

Duration

6 days

Interactions

None mentioned

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
nitrate supplementation
increase
exercise performance
-
-
can improve
#1
high-nitrate diet
increase
nitric oxide bioavailability
Seven healthy male subjects
-
increases
#2
high-nitrate diet
increase
Plasma nitrate concentrations
Seven healthy male subjects
127 ± 64 µM vs 23 ± 10 µM
significantly higher
#3
high-nitrate diet
increase
Plasma nitrite concentrations
Seven healthy male subjects
350 ± 120 nM vs 240 ± 100 nM
significantly higher
#4
high-nitrate diet
decrease
oxygen consumption during moderate-intensity constant work-rate cycling exercise
Seven healthy male subjects
1.178 ± 0.141 vs. 1.269 ± 0.136 L·min(-1)
significant reduction
#5
high-nitrate diet
increase
total muscle work during fatiguing, intermittent sub-maximal isometric knee extension
Seven healthy male subjects
357.3 ± 176.1 vs. 253.6 ± 149.0 Nm·s·kg(-1)
significantly higher
#6
high-nitrate diet
increase
performance in Repeated Sprint Ability test
Seven healthy male subjects
-
improved
#7
high-nitrate diet
increase
exercise performance
-
-
could be a feasible and effective strategy to improve
#8
Abstract

It has been reported that nitrate supplementation can improve exercise performance. Most of the studies have used either beetroot juice or sodium nitrate as a supplement; there is lack of data on the potential ergogenic benefits of an increased dietary nitrate intake from a diet based on fruits and vegetables. Our aim was to assess whether a high-nitrate diet increases nitric oxide bioavailability and to evaluate the effects of this nutritional intervention on exercise performance. Seven healthy male subjects participated in a randomized cross-over study. They were tested before and after 6 days of a high (HND) or control (CD) nitrate diet (~8.2 mmol∙day(-1) or ~2.9 mmol∙day(-1), respectively). Plasma nitrate and nitrite concentrations were significantly higher in HND (127 ± 64 µM and 350 ± 120 nM, respectively) compared to CD (23 ± 10 µM and 240 ± 100 nM, respectively). In HND (vs. CD) were observed: (a) a significant reduction of oxygen consumption during moderate-intensity constant work-rate cycling exercise (1.178 ± 0.141 vs. 1.269 ± 0.136 L·min(-1)); (b) a significantly higher total muscle work during fatiguing, intermittent sub-maximal isometric knee extension (357.3 ± 176.1 vs. 253.6 ± 149.0 Nm·s·kg(-1)); (c) an improved performance in Repeated Sprint Ability test. These findings suggest that a high-nitrate diet could be a feasible and effective strategy to improve exercise performance.

Medical Subject Headings (MeSH)
AdultBicyclingCross-Over StudiesDiet, HealthyExercise TestExercise ToleranceFruitHumansIsometric ContractionItalyMaleMuscle FatigueMuscle StrengthMuscle, SkeletalNitratesNitric OxideNitritesOxygen ConsumptionTime FactorsVegetablesYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations48
Citations/Year5.3
Relative Citation Ratio2.59
NIH Percentile81.6%
Research Impact Scores
APT Score0.95
Weight Score1.78
Normalized Score0.69
Related Supplements
Effects of a Short-Term High-Nitrate Diet on Exercise Perfor... | Panacea Index