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Feasibility of a physical activity intervention for obese, socioculturally diverse endometrial cancer survivors.

Gynecologic oncology
August 1, 2016
Amerigo Rossi et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the feasibility and effectiveness of a 12-week physical activity intervention, including home-based walking, on physical activity behavior, physical function, waist circumference, and quality of life in obese, socioculturally diverse endometrial cancer survivors.

Results Summary

The intervention showed large effect sizes for improvements in the six-minute walk test, waist circumference, quality of life, and walking self-efficacy compared to the control group, with participants reporting walking 118±79 minutes per week at home.

Population

Obese endometrial cancer survivors from Bronx, NY (38% non-Hispanic black, 38% Hispanic, 19% non-Hispanic white).

Effective Dosage

118±79 minutes/week of home-based walking.

Duration

12 weeks.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
12-week physical activity intervention of behavioral counseling, physical activity and home-based walking
increase
six-minute walk test
obese, socioculturally diverse endometrial cancer survivors
22±17m vs. 1±22m, d=1.10
improvements
#1
12-week physical activity intervention of behavioral counseling, physical activity and home-based walking
decrease
waist circumference
obese, socioculturally diverse endometrial cancer survivors
-5.3±5.3cm vs. 2.6±6.7cm, d=-1.32
improvements
#2
12-week physical activity intervention of behavioral counseling, physical activity and home-based walking
increase
quality of life
obese, socioculturally diverse endometrial cancer survivors
10±12 vs. -1±11, d=0.86
improvements
#3
12-week physical activity intervention of behavioral counseling, physical activity and home-based walking
increase
walking self-efficacy
obese, socioculturally diverse endometrial cancer survivors
24±30% vs. 1±55%, d=0.87
improvements
#4
Abstract

PURPOSE: Determine the feasibility of a 12-week physical activity intervention for obese, socioculturally diverse endometrial cancer survivors and to evaluate whether the intervention improves physical activity behavior, physical function, waist circumference, and quality of life. METHODS: Obese endometrial cancer survivors from Bronx, NY were assigned to either a 12-week physical activity intervention of behavioral counseling, physical activity and home-based walking (n=25), or wait-list control group (n=15). Mixed-design ANOVA (2 groups×2 time points) were analyzed to determine differences between the intervention and the control for the Yale Physical Activity Survey, six-minute walk test, 30-second chair stand test, waist circumference, and Functional Assessment of Cancer Therapy-Endometrial questionnaire. Data are presented as mean±standard deviation. RESULTS: The sample was diverse (38% non-Hispanic black, 38% Hispanic, 19% non-Hispanic white). Mean Body Mass Index was 37.3±6.5kg·m(-2). Although recruitment rate was low (20% of 140 contacted), 15 of 25 participants in the intervention group attended 75-100% of scheduled sessions. Participants reported walking 118±79min/week at home. There were large effect sizes for the improvements in the six-minute walk test (22±17m vs. 1±22m, d=1.10), waist circumference (-5.3±5.3cm vs. 2.6±6.7cm, d=-1.32), quality of life (10±12 vs. -1±11, d=0.86) and walking self-efficacy (24±30% vs. 1±55%, d=0.87) compared to the control group. CONCLUSIONS: The intervention appeared feasible in this population. The results show promising effects on several outcomes that should be confirmed in a larger randomized control trial, with more robust recruitment strategies.

Medical Subject Headings (MeSH)
AgedEndometrial NeoplasmsExerciseFeasibility StudiesFemaleHumansMiddle AgedNeoplasm StagingObesityQuality of LifeSocioeconomic FactorsSurvivorsWaiting Lists
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations33
Citations/Year3.7
Relative Citation Ratio1.24
NIH Percentile58.1%
Research Impact Scores
APT Score0.75
Weight Score1.86
Normalized Score0.69
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