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Acupuncture for dysmenorrhoea.

The Cochrane database of systematic reviews
January 1, 1970
Caroline A Smith et al. (6 authors)
Journal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov'tReviewSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to determine the effectiveness and safety of acupressure in treating primary dysmenorrhoea compared to sham/placebo, no treatment, or conventional medical treatment.

Results Summary

The study found inconsistent and inconclusive evidence for acupressure's effectiveness in reducing pain, with low-quality evidence overall. No adverse events were reported in any acupressure studies.

Population

Women of reproductive age with primary dysmenorrhoea experiencing moderate to severe symptoms during the majority of menstrual cycles or for three consecutive cycles.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
acupuncture
no change
pain
women of reproductive age with primary dysmenorrhoea
-
no evidence of a difference between the groups
#1
acupuncture
decrease
visual analogue scale (VAS) pain scores
women of reproductive age with primary dysmenorrhoea
0.64 to 4 points on a VAS 0 - 10 scale
scores were lower in the acupuncture group
#2
acupuncture
increase
rates of pain relief
women of reproductive age with primary dysmenorrhoea
OR 4.99, 95% CI 2.82 to 8.82
found a benefit for the acupuncture group
#3
acupuncture
decrease
adverse events
women of reproductive age with primary dysmenorrhoea
OR 0.10, 95% CI 0.02 to 0.44
less common in the acupuncture group
#4
acupuncture
decrease
pain
women of reproductive age with primary dysmenorrhoea
-
pain scores were lower in the acupuncture group
#5
acupressure
decrease
VAS pain scale
women of reproductive age with primary dysmenorrhoea
one to three points on a 0 - 10 VAS pain scale
reported a mean benefit
#6
acupressure
decrease
pain
women of reproductive age with primary dysmenorrhoea
-
pain scores were lower in the acupuncture group
#7
acupressure
increase
pain
women of reproductive age with primary dysmenorrhoea
MD 0.39 points, 95% CI 0.21 to 0.57
score was higher (indicating more pain) in the acupressure group
#8
acupressure
no change
VAS 0 - 10 pain scale
women of reproductive age with primary dysmenorrhoea
MD -0.96 points, 95% CI -2.54 to 0.62
no clear evidence of a difference between the groups
#9
Abstract

BACKGROUND: Primary dysmenorrhoea is the most common form of period pain and affects up to three-quarters of women at some stage of their reproductive life. Primary dysmenorrhoea is pain in the absence of any organic cause and is characterised by cramping pain in the lower abdomen, starting within the first eight to 72 hours of menstruation.This review examines the currently available evidence supporting the use of acupuncture (stimulation of points on the body using needles) and acupressure (stimulation of points on the body using pressure) to treat primary dysmenorrhoea. OBJECTIVES: To determine the effectiveness and safety of acupuncture and acupressure in the treatment of primary dysmenorrhoea when compared with a placebo, no treatment, or conventional medical treatment. SEARCH METHODS: We searched the following databases: the Cochrane Menstrual Disorders and Subfertility Group Trials Register (to September 2015), Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library), MEDLINE, EMBASE, PsycINFO, CINAHL and Chinese databases including Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), VIP database and registers of ongoing trials. SELECTION CRITERIA: We included all published and unpublished randomised controlled trials (RCTs) comparing acupuncture with sham acupuncture or placebo control, usual care, pharmacological treatment or no treatment. We included the following modes of treatment: acupuncture, electro-acupuncture, and acupressure. Participants were women of reproductive age with primary dysmenorrhoea during the majority of the menstrual cycles or for three consecutive menstrual cycles, and moderate to severe symptoms. DATA COLLECTION AND ANALYSIS: We calculated odds ratios (ORs) for dichotomous outcomes and mean differences (MDs) or standardised mean differences (SMDs) for continuous outcomes, with 95% confidence intervals (CIs). We pooled the data where appropriate. Our primary outcomes was pain. Secondary outcomes included menstrual symptoms, quality of life, and adverse effects. MAIN RESULTS: We included 42 RCTs (4640 women). Acupuncture or acupressure was compared with a sham/placebo group, medication, no treatment or other treatment. Many of the continuous data were not suitable for calculation of means, mainly due to evidence of skew.1. Acupuncture studies Acupuncture versus sham or placebo control (6 RCTs)Findings were inconsistent and inconclusive. However, the only study in the review that was at low risk of bias in all domains found no evidence of a difference between the groups at three, six or 12 months. The overall quality of the evidence was low. No studies reported adverse events. Acupuncture versus NSAIDs Seven studies reported visual analogue scale (VAS) pain scores, but were unsuitable for pooling due to extreme heterogeneity (I² = 94%). In all studies the scores were lower in the acupuncture group, with the mean difference varying across studies from 0.64 to 4 points on a VAS 0 - 10 scale (low-quality evidence). Four RCTs reported rates of pain relief, and found a benefit for the acupuncture group (OR 4.99, 95% CI 2.82 to 8.82, 352 women, I² = 0%, low-quality evidence). Adverse events were less common in the acupuncture group (OR 0.10, 95% CI 0.02 to 0.44, 4 RCTs, 239 women, 4 trials, I² = 15%, low-quality evidence). Acupuncture versus no treatment Data were unsuitable for analysis, but pain scores were lower in the acupuncture group in all six studies reporting this outcome. The quality of the evidence was low. No studies reported adverse events.2. Acupressure studiesNo studies of acupressure reported adverse events. Acupressure versus sham or placebo controlData were unsuitable for pooling, but two studies reported a mean benefit of one to three points on a 0 - 10 VAS pain scale. Another four studies reported data unsuitable for analysis: all found that pain scores were lower in the acupuncture group. No studies reported adverse events. The quality of the evidence was low. Acupressure versus NSAIDsOne study reported this outcome, using a 0 - 3 pain scale. The score was higher (indicating more pain) in the acupressure group (MD 0.39 points, 95% CI 0.21 to 0.57, 136 women, very low-quality evidence). Acupressure versus no treatmentThere was no clear evidence of a difference between the groups on a VAS 0 - 10 pain scale (MD -0.96 points, 95% CI -2.54 to 0.62, 2 trials, 140 women, I² = 83%, very low-quality evidence). AUTHORS' CONCLUSIONS: There is insufficient evidence to demonstrate whether or not acupuncture or acupressure are effective in treating primary dysmenorrhoea, and for most comparisons no data were available on adverse events. The quality of the evidence was low or very low for all comparisons. The main limitations were risk of bias, poor reporting, inconsistency and risk of publication bias.

Medical Subject Headings (MeSH)
Acupuncture TherapyAdolescentAdultAnti-Inflammatory Agents, Non-SteroidalDysmenorrheaFemaleHumansMiddle AgedRandomized Controlled Trials as TopicYoung Adult
Study Links
Quality Scores
Safety90
Efficacy45/10
Quality60/10
Citation Metrics
Total Citations62
Citations/Year6.9
Relative Citation Ratio4.23
NIH Percentile91%
Research Impact Scores
APT Score0.95
Weight Score1.60
Normalized Score0.66
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