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Are cardiovascular and metabolic responses to field walking tests interchangeable and obesity-dependent?

Disability and rehabilitation
September 1, 2016
Luciana Di Thommazo-Luporini et al. (9 authors)
Journal ArticleObservational StudyHuman StudyClinical
Study Details

Study Goal

To determine if the six-minute walk test (6MWT) and incremental shuttle walking test (ISWT) produce cardiovascular and metabolic responses comparable to cardiopulmonary exercise testing (CPX) and if they are interchangeable in obese and eutrophic individuals.

Results Summary

The study found agreement between CPX and both 6MWT and ISWT in obese women, with strong correlations between key variables (VO2, dyspnoea, and leg fatigue). The tests showed similar cardiovascular and metabolic responses in obese women but not in controls, suggesting interchangeability in clinical settings for this population.

Population

51 obese women (ObG) and 21 controls (CG), aged 20-45 years.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
six-minute walk test (6MWT)
no change
cardiovascular and metabolic responses
obese and eutrophic individuals
VO2 mL kg(-1) min(-1)) = 6.9 (CI: 5.7-8.1), and heart rate (bpm) = 37.0 (CI: 33.3-40.7)
agreement with
#1
incremental shuttle walking test (ISWT)
no change
cardiovascular and metabolic responses
obese and eutrophic individuals
VO2 (mL kg(-1) min(-1)) = 6.1 (CI: 4.9-7.3), and heart rate (bpm) = 36.2 (CI: 32.1-40.3)
agreement with
#2
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
no change
cardiovascular and metabolic responses
ObG (obese women)
-
similar cardiovascular and metabolic responses to both tests
#3
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
no change
cardiovascular and metabolic responses
CG (controls)
-
not similar cardiovascular and metabolic responses to both tests
#4
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
increase
VO2
-
r = 0.70
strong correlations were demonstrated between
#5
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
increase
dyspnoea
-
r = 0.80
strong correlations were demonstrated between
#6
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
increase
leg fatigue
-
r = 0.70
strong correlations were demonstrated between
#7
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
no change
clinical value
obese women
-
hold interchangeable clinical value when contrasted with
#8
six-minute walk test (6MWT) and incremental shuttle walking test (ISWT)
no change
clinical application
-
-
may be a viable alternative in the clinical setting
#9
walking field tests
no change
functional capacity
-
-
may be a cost-effective approach that provides valuable information regarding the functional capacity in agreement to
#10
Abstract

PURPOSE: To investigate if cardiovascular and metabolic responses to the six-minute walk test (6MWT) and incremental shuttle walking test (ISWT) are in agreement with cardiopulmonary exercise testing (CPX) and determine if both submaximal tests are interchangeable in obese and eutrophic individuals. METHOD: Observational and cross-sectional study included 51 obese women (ObG) and 21 controls (CG) (20-45 years old). Subjects underwent clinical evaluation, CPX, the 6MWT and ISWT. We applied Bland-Altman plots to assess agreement between walking tests and CPX. Correlation analysis assessed relationships between key variables. RESULTS: There was an agreement between CPX and both the 6MWT [oxygen uptake (VO2 mL kg(-1) min(-1)) = 6.9 (CI: 5.7-8.1), and heart rate (bpm) = 37.0 (CI: 33.3-40.7)] and ISWT [VO2 (mL kg(-1) min(-1)) = 6.1 (CI: 4.9-7.3), and heart rate (bpm) = 36.2 (CI: 32.1-40.3)]. We found similar cardiovascular and metabolic responses to both tests in the ObG but not in the CG. Strong correlations were demonstrated between 6MWT and ISWT variables: VO2 ( r = 0.70); dyspnoea (r = 0.80); and leg fatigue (r = 0.70). CONCLUSIONS: 6MWT and ISWT may both hold interchangeable clinical value when contrasted with CPX in obese women and may be a viable alternative in the clinical setting when resources and staffing are limited. Implications for Rehabilitation Obesity is a worldwide epidemic, with high prevalence in women, and it is associated to impaired cardiorespiratory fitness and functional capacity as well as high mortality risk. Assessing oxygen uptake by means of cardiopulmonary exercise testing is the gold standard method for evaluating and stratifying cardiorespiratory fitness, however it is not ever applied due to costs and staffing. Walking field tests may be a cost-effective approach that provides valuable information regarding the functional capacity in agreement to metabolic and cardiovascular responses of cardiopulmonary exercise testing.

Medical Subject Headings (MeSH)
AdultBrazilCase-Control StudiesCross-Sectional StudiesDyspneaExercise ToleranceFatigueFemaleHeart RateHumansObesityOxygen ConsumptionWalk Test
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations6
Citations/Year0.7
Relative Citation Ratio0.32
NIH Percentile17.1%
Research Impact Scores
APT Score0.25
Weight Score1.64
Normalized Score0.69
Related Supplements
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