Mindfulness-based Stress Reduction (MBSR) as Treatment for Chronic Back Pain - an Observational Study with Assessment of Thalamocortical Dysrhythmia.
Study Goal
The researchers aimed to assess the feasibility and effectiveness of an 8-week MBSR program for chronic low back pain patients, including changes in thalamocortical dysrhythmia.
Results Summary
The study found medium effect sizes for improvements in quality of life, psychological functioning, depression, and affective pain perception, but no significant EEG changes post-intervention. Pain severity measurements showed moderate improvements.
Population
22 patients with chronic low back pain.
Effective Dosage
Not specified
Duration
8 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
8-week mindfulness-based stress reduction (MBSR) program | increase | health-related quality of life (EQ-5D, VAS) | patients with chronic low back pain | d = 0.43, p = 0.02 | medium size effect sizes were found | #1 |
8-week mindfulness-based stress reduction (MBSR) program | increase | health-related quality of life (SF-12, psychological functioning) | patients with chronic low back pain | d = 0.50, p = 0.05 | medium size effect sizes were found | #2 |
8-week mindfulness-based stress reduction (MBSR) program | increase | health-related life satisfaction | patients with chronic low back pain | d = 0.69, p = 0.01 | medium size effect sizes were found | #3 |
8-week mindfulness-based stress reduction (MBSR) program | decrease | depression (HADS) | patients with chronic low back pain | d = 0.48, p = 0.04 | medium size effect sizes were found | #4 |
8-week mindfulness-based stress reduction (MBSR) program | decrease | depression (Brief Symptom Inventory) | patients with chronic low back pain | d = 0.41, p = 0.04 | medium size effect sizes were found | #5 |
8-week mindfulness-based stress reduction (MBSR) program | decrease | affective pain perception (pain perception scale) | patients with chronic low back pain | d = 0.50, p = 0.04 | medium size effect sizes were found | #6 |
8-week mindfulness-based stress reduction (MBSR) program | decrease | pain severity measurements | patients with chronic low back pain | d = 0.45-0.75 (p = 0.01-0.24) | improved | #7 |
8-week mindfulness-based stress reduction (MBSR) program | no change | EEG power spectral density parameters | patients with chronic low back pain | no differences between the pre- and post-intervention | revealed no differences | #8 |
BACKGROUND: A pilot study of an 8-week mindfulness-based stress reduction (MBSR) program on a sample of low back pain patients was conducted in order to assess the feasibility and effectiveness of the intervention as well as changes in an EEG pattern called thalamocortical dysrhythmia which is associated with chronic pain. PATIENTS AND METHODS: 22 patients with chronic low back pain participated in an MBSR program. Effect sizes were measured for psychological functioning, pain severity, and quality of life. Furthermore, 4 parameters of the EEG power spectral density were assessed. RESULTS: Medium size effect sizes were found for health-related quality of life (EQ-5D, VAS, d = 0.43, p = 0.02; SF-12, psychological functioning, d = 0.50, p = 0.05), health-related life satisfaction (questions on life satisfaction d = 0.69, p = 0.01), depression (HADS, d = 0.48, p = 0.04, Brief Symptom Inventory d = 0.41, p = 0.04), and affective pain perception (pain perception scale d = 0.50, p = 0.04). The most relevant pain severity measurements improved in the range of d = 0.45-0.75 (p = 0.01-0.24). EEG analyses revealed no differences between the pre- and post-intervention. CONCLUSION: MBSR is a feasible intervention for patients with low back pain. They benefit from medium size effects which are comparable to similar behavioral interventions. Randomized controlled trials are needed in order to determine the specificity of these benefits.