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Nutritional Impact of a Gluten-Free Casein-Free Diet in Children with Autism Spectrum Disorder.

Journal of autism and developmental disorders
February 1, 2016
Salvador Marí-Bauset et al. (5 authors)
Controlled Clinical TrialJournal ArticleHuman StudyClinical
Study Details

Study Goal

The researchers compared nutrient intake, including calcium, between children with autism spectrum disorder (ASD) on a gluten-free casein-free (GFCF) diet and those on a regular diet.

Results Summary

The GFCF diet group had lower calcium intake compared to the regular diet group, but the study did not assess calcium's direct effects or outcomes. The abstract suggests further research is needed to explore long-term nutritional impacts.

Population

Children with autism spectrum disorder (ASD) in Valencia, Spain (20 on GFCF diet, 85 on regular diet).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (12)
InterventionDirectionEndpointPopulationDosageImpactClaim #
gluten-free casein-free (GFCF) diet
decrease
weight
children with autism spectrum disorder (ASD)
-
had a lower
#1
gluten-free casein-free (GFCF) diet
decrease
body mass index
children with autism spectrum disorder (ASD)
-
had a lower
#2
gluten-free casein-free (GFCF) diet
decrease
total energy intake
children with autism spectrum disorder (ASD)
-
had a lower
#3
gluten-free casein-free (GFCF) diet
decrease
pantothenic acid intake
children with autism spectrum disorder (ASD)
-
had a lower
#4
gluten-free casein-free (GFCF) diet
decrease
calcium intake
children with autism spectrum disorder (ASD)
-
had a lower
#5
gluten-free casein-free (GFCF) diet
decrease
phosphorus intake
children with autism spectrum disorder (ASD)
-
had a lower
#6
gluten-free casein-free (GFCF) diet
decrease
sodium intake
children with autism spectrum disorder (ASD)
-
had a lower
#7
gluten-free casein-free (GFCF) diet
increase
fiber
children with autism spectrum disorder (ASD)
-
had a higher intake of
#8
gluten-free casein-free (GFCF) diet
increase
legumes
children with autism spectrum disorder (ASD)
-
had a higher intake of
#9
gluten-free casein-free (GFCF) diet
increase
vegetables
children with autism spectrum disorder (ASD)
-
had a higher intake of
#10
gluten-free casein-free (GFCF) diet
increase
quality of fat intake
children with autism spectrum disorder (ASD)
-
had a better
#11
gluten-free casein-free (GFCF) diet
neutral
vitamin D
children with autism spectrum disorder (ASD)
-
needed supplementation with
#12
Abstract

We compared anthropometric values, nutrient intake, the Healthy Eating Index and food variety in children with autism spectrum disorder (ASD), 20 on a gluten-free casein-free (GFCF) diet and 85 on a regular diet in Valencia (Spain) using 3-days food diaries. Those on the GFCF diet had a lower weight, body mass index, and total energy, pantothenic acid, calcium, phosphorus and sodium intake, but a higher intake of fiber, legumes, and vegetables. Further, the GFCF diet group had a better quality of fat intake, but needed supplementation with vitamin D. Randomized controlled trials are required to explore long-term effects of this diet on anthropometric and nutritional status (the focus of our study), but also behavioral symptoms, in children with ASD.

Medical Subject Headings (MeSH)
Autism Spectrum DisorderCaseinsChildDiet, Gluten-FreeDietary SupplementsFemaleHumansMaleNutritional Status
Study Links
Quality Scores
SafetyNot Assessed
Efficacy30/10
Quality65/10
Citation Metrics
Total Citations25
Citations/Year2.8
Relative Citation Ratio1.28
NIH Percentile59.3%
Research Impact Scores
APT Score0.75
Weight Score1.67
Normalized Score0.45
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