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Low-level laser therapy (LLLT) associated with aerobic plus resistance training to improve inflammatory biomarkers in obese adults.

Lasers in medical science
July 1, 2015
Raquel Munhoz da Silveira Campos et al. (9 authors)
Clinical TrialJournal ArticleResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the effects of combining low-level laser therapy (LLLT) with aerobic and resistance training on inflammatory profile and body composition in obese women.

Results Summary

The study found that LLLT combined with physical exercise was more effective than exercise alone in increasing adiponectin (an anti-inflammatory adipokine) and reducing neck circumference, insulin concentration, and interleukin-6 levels. These results suggest LLLT may help attenuate inflammation and improve body composition in obese women.

Population

40 obese women aged 20-40 with a BMI between 30-40 kg/m².

Effective Dosage

808 nm phototherapy applied immediately after physical exercise (specific dosage not detailed).

Duration

Not specified in the abstract.

Interactions

None mentioned.

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-level laser (light) therapy (LLLT)
neutral
noninvasive treatment of cellulite, improvement of body countering, and control of lipid profile
-
-
suggest the benefits
#1
aerobic plus resistance training
decrease
body fat and inflammatory process
obese women
-
reduce
#2
combined therapy of LLLT and aerobic plus resistance training
neutral
inflammatory profile and body composition
obese women
-
evaluate the effects
#3
LLLT associated to physical exercise
increase
adiponectin concentration
-
-
is more effective than physical exercise alone to increase
#4
LLLT
decrease
neck circumference
-
-
showed reduced values
#5
LLLT
decrease
insulin concentration
-
-
showed reduced values
#6
LLLT
decrease
interleukin-6
-
-
showed reduced values
#7
phototherapy
neutral
obesity
-
-
can be an important tool
#8
phototherapy associated to exercise training
decrease
inflammation
women
-
potential effects in attenuating
#9
Abstract

Recently, investigations suggest the benefits of low-level laser (light) therapy (LLLT) in noninvasive treatment of cellulite, improvement of body countering, and control of lipid profile. However, the underlying key mechanism for such potential effects associated to aerobic plus resistance training to reduce body fat and inflammatory process, related to obesity in women still unclear. The purpose of the present investigation was to evaluate the effects of combined therapy of LLLT and aerobic plus resistance training in inflammatory profile and body composition of obese women. For this study, it involved 40 obese women with age of 20-40 years. Inclusion criteria were primary obesity and body mass index (BMI) greater than 30 kg/m(2) and less than 40 kg/m(2). The voluntaries were allocated in two different groups: phototherapy group and SHAM group. The interventions consisted on physical exercise training and application of phototherapy (808 nm), immediately after the physical exercise, with special designed device. Proinflammatory/anti-inflammatory adipokines were measured. It was showed that LLLT associated to physical exercise is more effective than physical exercise alone to increase adiponectin concentration, an anti-inflammatory adipokine. Also, it showed reduced values of neck circumference (cm), insulin concentration (μU/ml), and interleukin-6 (pg/ml) in LLLT group. In conclusion, phototherapy can be an important tool in the obesity, mostly considering its potential effects associated to exercise training in attenuating inflammation in women, being these results applicable in the clinical practices to control related risk associated to obesity.

Medical Subject Headings (MeSH)
AdiponectinAdipose TissueAdultBiomarkersBody Mass IndexCombined Modality TherapyFemaleHumansInflammation MediatorsInsulinInterleukin-6Lasers, SemiconductorLipidsLow-Level Light TherapyObesityResistance TrainingTreatment OutcomeWeight LossYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations19
Citations/Year1.9
Relative Citation Ratio1.00
NIH Percentile50.2%
Research Impact Scores
APT Score0.50
Weight Score1.67
Normalized Score0.69
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