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Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial.

BMC psychiatry
January 1, 1970
Adoración Castro et al. (11 authors)
Journal ArticleMulticenter StudyRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to assess the efficacy of a mindfulness-based intervention delivered via ICTs for treating mild to moderate depression in primary care settings.

Results Summary

The study found that mindfulness, along with other low-intensity psychological interventions, showed significant efficacy for depression treatment in specialized clinical settings, though ICT-based delivery was not previously tested. The trial will evaluate its effectiveness in primary care using a randomized controlled design.

Population

Mild and moderate depressed patients in Primary Care settings (N=240).

Effective Dosage

One face-to-face session and four online modules (specific duration/frequency not detailed).

Duration

Assessments at baseline, post-treatment, 6 months, and 12 months post-treatment (exact intervention duration not specified).

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-intensity psychological interventions applied by Information and Communication Technologies (ICTs)
decrease
depression treatment
patients with depression
-
could be an efficacious and cost-effective therapeutic option
#1
healthy lifestyle psychoeducational program
decrease
depression treatment
mild and moderate depressed patients
-
significant efficacy for depression treatment has previously showed
#2
focused program on positive affect promotion
decrease
depression treatment
mild and moderate depressed patients
-
significant efficacy for depression treatment has previously showed
#3
mindfulness
decrease
depression treatment
mild and moderate depressed patients
-
significant efficacy for depression treatment has previously showed
#4
Abstract

BACKGROUND: Depression is one of the most common disorders in Psychiatric and Primary Care settings and is associated with significant disability and economic costs. Low-intensity psychological interventions applied by Information and Communication Technologies (ICTs) could be an efficacious and cost-effective therapeutic option for the treatment of depression. The aim of this study is to assess 3 low-intensity psychological interventions applied by ICTs (healthy lifestyle, positive affect and mindfulness) in Primary Care; significant efficacy for depression treatment has previously showed in specialized clinical settings by those interventions, but ICTs were not used. METHOD: Multicenter controlled randomized clinical trial in 4 parallel groups. Interventions have been designed and on-line device adaptation has been carried out. Subsequently, the randomized controlled clinical trial will be conducted. A sample of N = 240 mild and moderate depressed patients will be recruited and assessed in Primary Care settings. Patients will be randomly assigned to a) healthy lifestyle psychoeducational program + improved primary care usual treatment (ITAU), b) focused program on positive affect promotion + ITAU c) mindfulness + ITAU or d) ITAU. The intervention format will be one face to face session and four ICTs on-line modules. Patients will be diagnosed with MINI psychiatric interview. Main outcome will be PHQ-9 score. They will be also assessed by SF-12 Health Survey, Client Service Receipt Inventory, EuroQoL-5D questionnaire, Positive and Negative Affect Scale, Five Facet Mindfulness Questionnaire and the Pemberton Happiness Index. Patients will be assessed at baseline, post, 6 and 12 post-treatment months. An intention to treat and per protocol analysis will be performed. DISCUSSION: Low-intensity psychological interventions applied by Information and Communication Technologies have been not used before in Spain and could be an efficacious and cost-effective therapeutic option for depression treatment. The strength of the study is that it is the first multicenter controlled randomized clinical trial of three low intensity and self-guided interventions applied by ICTs (healthy lifestyle psychoeducational program; focused program on positive affect promotion and brief intervention based on mindfulness) in Primary Care settings. TRIAL REGISTRATION: Current Controlled Trials ISRCTN82388279 . Registered 16 April 2014.

Medical Subject Headings (MeSH)
AdultClinical ProtocolsDepressionFemaleHealth PromotionHumansMaleMindfulnessPrimary Health CarePsychotherapyTherapy, Computer-AssistedYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations14
Citations/Year1.4
Relative Citation Ratio0.81
NIH Percentile42.6%
Research Impact Scores
APT Score0.50
Weight Score1.76
Normalized Score0.67
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