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Managing Knee Osteoarthritis: The Effects of Body Weight Supported Physical Activity on Joint Pain, Function, and Thigh Muscle Strength.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
November 1, 2015
Jason Peeler et al. (5 authors)
Journal ArticleObservational StudyResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

To determine the effect of a 12-week LBPP-supported low-load treadmill walking program on knee joint pain, function, and thigh muscle strength in overweight patients with knee osteoarthritis.

Results Summary

Participants reported significant improvements in knee joint pain and function, demonstrated increased thigh muscle strength, and required less LBPP support to walk pain-free. The regimen effectively reduced acute knee pain during walking and improved daily joint symptoms.

Population

Overweight patients aged 55-75 with mild-to-moderate knee osteoarthritis (BMI ≥25 kg/m).

Effective Dosage

LBPP-supported low-load treadmill walking (specific frequency not detailed).

Duration

12 weeks.

Interactions

None mentioned.

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
12-week LBPP-supported low-load treadmill walking regimen
decrease
knee joint pain and function
overweight patients with knee osteoarthritis (OA)
-
significant improvements
#1
12-week LBPP-supported low-load treadmill walking regimen
increase
thigh muscle strength about the degenerative knee
overweight patients with knee osteoarthritis (OA)
-
significant increases
#2
12-week LBPP-supported low-load treadmill walking regimen
decrease
acute knee pain during full weight bearing treadmill walking
overweight patients with knee osteoarthritis (OA)
-
significant reductions
#3
12-week LBPP-supported low-load treadmill walking regimen
decrease
LBPP support to walk pain free on the treadmill
overweight patients with knee osteoarthritis (OA)
-
dramatically less
#4
LBPP-supported low-load exercise regimen
decrease
knee pain
overweight patients with knee OA
-
significantly diminish
#5
LBPP-supported low-load exercise regimen
increase
joint function
overweight patients with knee OA
-
enhance
#6
LBPP-supported low-load exercise regimen
increase
thigh muscle strength
overweight patients with knee OA
-
increase
#7
LBPP-supported low-load exercise regimen
increase
pain-free walking exercise
overweight patients with knee OA
-
safely promoting
#8
LBPP-supported low-load walking
increase
the physical health, quality of life, and social well-being
North America's aging population
-
helping to improve
#9
Abstract

OBJECTIVE: To determine the effect of a 12-week lower body positive pressure (LBPP)-supported low-load treadmill walking program on knee joint pain, function, and thigh muscle strength in overweight patients with knee osteoarthritis (OA). DESIGN: Prospective, observational, repeated measures investigation. SETTING: Community-based, multidisciplinary sports medicine clinic. PATIENTS: Thirty-one patients aged between 55 and 75 years, with a body mass index ≥25 kg/m and mild-to-moderate knee OA. INTERVENTION: Twelve-week LBPP-supported low-load treadmill walking regimen. MAIN OUTCOME MEASURES: Acute knee joint pain (visual analog scale) during full weight bearing treadmill walking, chronic knee pain, and joint function [Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire] during normal activities of daily living, and thigh muscle strength (isokinetic testing). Appropriate methods of statistical analysis were used to compare data from baseline and follow-up evaluation. RESULTS: Participants reported significant improvements in knee joint pain and function and demonstrated significant increases in thigh muscle strength about the degenerative knee. Participants also experienced significant reductions in acute knee pain during full weight bearing treadmill walking and required dramatically less LBPP support to walk pain free on the treadmill. CONCLUSIONS: Data suggest that an LBPP-supported low-load exercise regimen can be used to significantly diminish knee pain, enhance joint function, and increase thigh muscle strength, while safely promoting pain-free walking exercise in overweight patients with knee OA. These findings have important implications for the development of nonoperative treatment strategies that can be used in the management of joint symptoms associated with progressive knee OA in at-risk patient populations. CLINICAL RELEVANCE: This research suggests that LBPP-supported low-load walking is a safe user-friendly mode of exercise that can be successfully used in the management of day-to-day joint symptoms associated with knee OA, helping to improve the physical health, quality of life, and social well-being of North America's aging population.

Medical Subject Headings (MeSH)
AgedBody WeightExercise TherapyFemaleHumansKnee JointMaleMiddle AgedMuscle StrengthOsteoarthritis, KneePainProspective StudiesQuadriceps MuscleWeight-Bearing
Study Links
Quality Scores
Safety85
Efficacy90/10
Quality80/10
Citation Metrics
Total Citations27
Citations/Year2.7
Relative Citation Ratio1.66
NIH Percentile68.7%
Research Impact Scores
APT Score0.75
Weight Score1.78
Normalized Score0.86
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Managing Knee Osteoarthritis: The Effects of Body Weight Sup... | Panacea Index