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The effect of walking on risk factors for cardiovascular disease: an updated systematic review and meta-analysis of randomised control trials.

Preventive medicine
March 1, 2015
Elaine M Murtagh et al. (6 authors)
Journal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov'tReviewSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to determine the effect of walking on cardiovascular disease risk factors through a systematic review and meta-analysis of randomized control trials.

Results Summary

Walking interventions significantly improved aerobic capacity, reduced blood pressure, waist circumference, weight, body fat percentage, and BMI, but did not affect blood lipids. The findings highlight walking as an effective health promotion activity.

Population

Inactive participants at baseline.

Effective Dosage

Not specified (walking as the only treatment).

Duration

Interventions ≥ 4 weeks.

Interactions

None mentioned.

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
walking interventions
increase
aerobic capacity
inactive participants
3.04 mL/kg/min
increased
#1
walking interventions
decrease
systolic blood pressure
inactive participants
-3.58 mm Hg
reduced
#2
walking interventions
decrease
diastolic blood pressure
inactive participants
-1.54 mm Hg
reduced
#3
walking interventions
decrease
waist circumference
inactive participants
-1.51 cm
reduced
#4
walking interventions
decrease
weight
inactive participants
-1.37 kg
reduced
#5
walking interventions
decrease
percentage body fat
inactive participants
-1.22%
reduced
#6
walking interventions
decrease
body mass index
inactive participants
-0.53 kg/m(2)
reduced
#7
walking interventions
no change
blood lipids
inactive participants
no significant change
failed to alter
#8
Abstract

OBJECTIVE: To conduct a systematic review and meta-analysis of randomised control trials that examined the effect of walking on risk factors for cardiovascular disease. METHODS: Four electronic databases and reference lists were searched (Jan 1971-June 2012). Two authors identified randomised control trials of interventions ≥ 4 weeks in duration that included at least one group with walking as the only treatment and a no-exercise comparator group. Participants were inactive at baseline. Pooled results were reported as weighted mean treatment effects and 95% confidence intervals using a random effects model. RESULTS: 32 articles reported the effects of walking interventions on cardiovascular disease risk factors. Walking increased aerobic capacity (3.04 mL/kg/min, 95% CI 2.48 to 3.60) and reduced systolic (-3.58 mm Hg, 95% CI -5.19 to -1.97) and diastolic (-1.54 mm Hg, 95% CI -2.83 to -0.26) blood pressure, waist circumference (-1.51 cm, 95% CI -2.34 to -0.68), weight (-1.37 kg, 95% CI -1.75 to -1.00), percentage body fat (-1.22%, 95% CI -1.70 to -0.73) and body mass index (-0.53 kg/m(2), 95% CI -0.72 to -0.35) but failed to alter blood lipids. CONCLUSIONS: Walking interventions improve many risk factors for cardiovascular disease. This underscores the central role of walking in physical activity for health promotion.

Medical Subject Headings (MeSH)
AdiposityBlood PressureBody Mass IndexCardiovascular DiseasesFemaleHumansLipidsMaleRandomized Controlled Trials as TopicRisk FactorsWaist CircumferenceWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations166
Citations/Year16.6
Relative Citation Ratio7.40
NIH Percentile96.4%
Research Impact Scores
APT Score0.95
Weight Score1.09
Normalized Score0.72
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