Study of the effects of a diet supplemented with active components on lipid and glycemic profiles.
Study Goal
The researchers aimed to evaluate the effects of Beta-glucans, among other functional components, on lipid profiles and postprandial glucose response in young, slightly overweight individuals with dyslipidemia or near-dyslipidemia.
Results Summary
The study found a statistically significant reduction in lipid profile markers and a significantly lower glycemic response after a meal enriched with Beta-glucans compared to a non-enriched meal.
Population
Young (20-37 years), slightly overweight individuals with normal glucose tolerance and dyslipidemia or near-dyslipidemia.
Effective Dosage
Not specified
Duration
4 weeks (run-in phase) plus intervention duration (not specified)
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
diet containing foods enriched with ω-3 fatty acids, β-glucans, phytosterols, and vitamin E | decrease | lipid profile | young, slightly overweight individuals with normal glucose tolerance and lipid values indicating dyslipidemia or close dyslipidemia | α < 0.05 | statistically significant reduction | #1 |
meal enriched with β-glucans | decrease | glycemic response | young, slightly overweight individuals with normal glucose tolerance and lipid values indicating dyslipidemia or close dyslipidemia | - | significantly lower | #2 |
dietary supplements based on the integration of functional components (ω-3 fatty acids, β-glucans, phytosterols, and vitamin E) into the usual diet | decrease | peak levels of postprandial glucose | the population | - | effective in reducing | #3 |
dietary supplements based on the integration of functional components (ω-3 fatty acids, β-glucans, phytosterols, and vitamin E) into the usual diet | decrease | risk for dyslipidemia | the population | - | effective in reducing | #4 |
functional components (ω-3 fatty acids, β-glucans, phytosterols, and vitamin E) | decrease | cardiovascular diseases and metabolic disorders | - | - | proved a valuable aid in the prevention of | #5 |
OBJECTIVES: Currently, there are numerous studies on risk factors for cardiovascular disease and the potential for functional foods to bring benefits or improve people's health. However, most of these studies are conducted with middle-aged individuals. The aim of this study was to evaluate the effects of supplementing a typical diet with some functional components, which are substances that when consumed in small quantities can improve people's welfare. METHODS: The participants in this study were young; slightly overweight; had normal glucose tolerance; and had lipid values indicating dyslipidemia or close dyslipidemia. Following a 4-wk run-in phase, participants followed either a diet containing foods enriched with ω-3 fatty acids, β-glucans, phytosterols, and vitamin E or an isoenergetic diet without the active components. Sixteen individuals (age range 20 to 37 y) were randomly assigned to one of two groups. At the end of treatment, while fasting, plasma concentrations of triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and total cholesterol were measured. Furthermore, blood glucose was evaluated after fasting and after a meal enriched with β-glucans. RESULTS: There was a statistically significant reduction (α < 0.05) across the lipid profile. A meal rich in β-glucans produced a glycemic response significantly lower than the nonenriched meal. CONCLUSION: The dietary supplements used in this work, based on the integration of functional components into the usual diet of the population, have proved effective in reducing peak levels of postprandial glucose and the risk for dyslipidemia. Therefore, these functional components proved a valuable aid in the prevention of cardiovascular diseases and metabolic disorders.