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The role of FODMAPs in irritable bowel syndrome.

Current opinion in clinical nutrition and metabolic care
November 1, 2014
Susan J Shepherd et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers compared the efficacy of a low FODMAP diet to a gluten-free diet in managing IBS symptoms, particularly in individuals with self-reported nonceliac gluten sensitivity.

Results Summary

The study found that the low FODMAP diet was superior to a gluten-free diet for symptom management in IBS patients with self-reported nonceliac gluten sensitivity. No significant adverse effects or safety concerns for the gluten-free diet were mentioned.

Population

Individuals with irritable bowel syndrome (IBS) and self-reported nonceliac gluten sensitivity.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low FODMAP diet
decrease
functional gastrointestinal symptoms seen in IBS
IBS patients
-
has been shown to be an efficacious therapy for reduction
#1
low FODMAP diet
increase
symptom management
people with self-reported nonceliac gluten sensitivity
-
appears to be superior
#2
low FODMAP diet
no change
prebiotic effect in the colon
-
-
has not been shown to reduce
#3
low FODMAP diet
decrease
total colonic bacterial load
-
-
was reduced
#4
Abstract

PURPOSE OF REVIEW: Irritable bowel syndrome (IBS) is a condition affecting approximately 10-15% of Western populations. The Rome III criteria are applied to many studies to validate the diagnosis of IBS. The low fermentable oligo, di, monosaccharides and polyol (FODMAP) diet has been the subject of many robust clinical trials and is now used as the primary dietary therapy internationally. This review examines the current evidence for the role of the low FODMAP diet in IBS. RECENT FINDINGS: Detailed commentary on original research involving FODMAPs and IBS symptoms from 2013 to 2014 is provided. SUMMARY: The low FODMAP diet has been shown to be an efficacious therapy for reduction of functional gastrointestinal symptoms seen in IBS. Recent publications provide randomized controlled trial and prospective observational evidence in support of the diet for symptom management. The low FODMAP diet appears to be superior to a gluten-free diet in people with self-reported nonceliac gluten sensitivity. Although the low FODMAP diet has not been shown to reduce the prebiotic effect in the colon, total colonic bacterial load was reduced. Further research investigating the potential health implications of both this and the nutritional adequacy of the liberalized low FODMAP diet is required.

Medical Subject Headings (MeSH)
ColonDietDiet, Gluten-FreeDisaccharidesFeeding BehaviorFermentationHumansIrritable Bowel SyndromeMonosaccharidesObservational Studies as TopicOligosaccharidesPolymersRandomized Controlled Trials as Topic
Study Links
Quality Scores
SafetyNot Assessed
Efficacy40/10
Quality75/10
Citation Metrics
Total Citations20
Citations/Year1.8
Relative Citation Ratio0.80
NIH Percentile42.1%
Research Impact Scores
APT Score0.50
Weight Score0.78
Normalized Score0.51
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