Caffeine modifies blood glucose availability during prolonged low-intensity exercise in individuals with type-2 diabetes.
Study Goal
The researchers aimed to investigate the effects of caffeine supplementation, alone or combined with maltodextrin, on blood glucose levels during exercise in individuals with type 2 diabetes.
Results Summary
Caffeine supplementation (1.5 mg/kg) significantly reduced blood glucose levels by 75 mg/dL (65%) during 40 minutes of exercise compared to other treatments, with no significant changes in blood pressure or heart rate.
Population
Eight subjects with type 2 diabetes, aged 55±10 years.
Effective Dosage
1.5 mg/kg of caffeine.
Duration
Single administration before a 40-minute exercise protocol.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
maltodextrin (CHO) alone or associated to caffeine | no change | blood pressure | T2DM subjects | - | did not change significantly | #1 |
maltodextrin (CHO) alone or associated to caffeine | no change | heart rate | T2DM subjects | - | did not change significantly | #2 |
caffeine | decrease | blood glucose | T2DM subjects | 75 mg/dL (65%) | promoted a significant reduction | #3 |
1.5 mg/kg of caffeine | decrease | blood glucose concentration | T2DM patients | - | reduces | #4 |
OBJECTIVE: The study investigated the effect of supplementation with maltodextrin (CHO) alone or associated to caffeine during exercise in T2DM subjects. METHODS: Pilot study, using eight subjects with T2DM, aged 55±10 years, received CHO (1 g/kg) or caffeine (1.5 mg/kg) alone or associated before exercise protocol. The exercise was executed at 40% heart rate (HR) reserve for 40 min, with 10-min recovery. Blood pressure (BP) and perceived exertion scale (Borg) were checked every 2 min. Blood glucose (BG) was checked every 10 min. For statistical analysis, ANOVA test was used and the value was considered statistically significant at p <0.05. RESULTS: The results showed that BP and HR did not change significantly among all treatments. Caffeine promoted a significant reduction in BG of 75 mg/dL (65%, p <0.05) during 40 min of exercise protocol compared to all groups. CONCLUSION: Supplementation with 1.5 mg/kg of caffeine reduces BG concentration during prolonged exercise in T2DM patients. OBJECTIVO: Investigar los efectos de la suplementación con maltodextrina (CHO) sólo o combinado con cafeína durante el ejercicio en sujetos con diabetes tipo 2 . MÉTODOS: Estudio piloto que incluyó ocho sujetos con DM2, de 55±10 años, el CHO (1g/kg) o cafeína (1.5 mg/kg) sólo o combinado antes del protocolo de ejercicio. El ejercicio se realizó a 40% de la frecuencia cardiaca (FC). Reserva del corazón durante 40 min con 10 min de recuperación. La presión arterial (PA) y la escala de esfuerzo (Borg) fueron revisadas cada 2 min. La glucosa en sangre (GS) se comprobó cada 10 min. El análisis estadístico se realizó mediante ANOVA, y consideró significación estadística un valor de RESULTADOS: Los resultados muestran que PA, FC y Borg no difirió significativamente entre los tratamientos. La cafeína promueve una reducción significativa en los niveles de glucosa en la sangre de 75 mg/dL (65%, CONCLUSIONES: Suplementación con 1.5 mg/kg de cafeína redujo significativamente los niveles de GS durante el protocolo de ejercicio en pacientes con DM2 .