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The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: a randomized controlled trial.

Psycho-oncology
April 1, 2015
Cecile A Lengacher et al. (12 authors)
Journal ArticleRandomized Controlled TrialResearch Support, N.I.H., ExtramuralHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the effects of mindfulness-based stress reduction (MBSR(BC)) on objective and subjective sleep parameters in breast cancer survivors.

Results Summary

MBSR(BC) showed significant improvements in objective sleep parameters (sleep efficiency, percent sleep time, and fewer waking bouts) at 12 weeks, with small nonsignificant improvements in subjective sleep parameters. No significant relationship was found between practice duration and sleep outcomes.

Population

Breast cancer survivors (stages 0-III), mean age 57 years.

Effective Dosage

6-week formal (in-class) MBSR(BC) program.

Duration

6 weeks with a 12-week follow-up.

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness-based stress reduction for breast cancer survivors (MBSR(BC))
increase
sleep efficiency
breast cancer survivors (BCS)
78.2% MBSR(BC) group versus 74.6% UC group
showed indications of a positive effect
#1
mindfulness-based stress reduction for breast cancer survivors (MBSR(BC))
increase
percent of sleep time
breast cancer survivors (BCS)
81.0% MBSR(BC) group versus 77.4% UC group
showed indications of a positive effect
#2
mindfulness-based stress reduction for breast cancer survivors (MBSR(BC))
decrease
number waking bouts
breast cancer survivors (BCS)
93.5 in MBSR(BC) group versus 118.6 in the UC group
showed indications of a positive effect
#3
mindfulness-based stress reduction for breast cancer survivors (MBSR(BC))
increase
subjective sleep parameters (SSP)
breast cancer survivors (BCS)
p = 0.09
Small nonsignificant improvements were found
#4
minutes of MBSR(BC) practice
no change
subjective sleep parameters (SSP)
breast cancer survivors (BCS)
-
No significant relationship was observed
#5
minutes of MBSR(BC) practice
no change
objective sleep parameters (OSP)
breast cancer survivors (BCS)
-
No significant relationship was observed
#6
Abstract

OBJECTIVE: The purpose of this study was to investigate the effects of mindfulness-based stress reduction for breast cancer survivors (MBSR(BC)) on multiple measures of objective and subjective sleep parameters among breast cancer survivors (BCS). METHODS: Data were collected using a two-armed randomized controlled design among BCS enrolled in either a 6-week MBSR(BC) program or a usual care (UC) group with a 12-week follow-up. The present analysis is a subset of the larger parent trial (ClinicalTrials.gov Identifier: NCT01177124). Seventy-nine BCS participants (mean age 57 years), stages 0-III, were randomly assigned to either the formal (in-class) 6-week MBSR(BC) program or UC. Subjective sleep parameters (SSP) (i.e., sleep diaries and the Pittsburgh Sleep Quality Index (PSQI)) and objective sleep parameters (OSP) (i.e., actigraphy) were measured at baseline, 6 weeks, and 12 weeks after completing the MBSR(BC) or UC program. RESULTS: Results showed indications of a positive effect of MBSR(BC) on OSP at 12 weeks on sleep efficiency (78.2% MBSR(BC) group versus 74.6% UC group, p = 0.04), percent of sleep time (81.0% MBSR(BC) group versus 77.4% UC group, p = 0.02), and less number waking bouts (93.5 in MBSR(BC) group versus 118.6 in the UC group, p < 0.01). Small nonsignificant improvements were found in SSP in the MBSR(BC) group from baseline to 6 weeks (PSQI total score, p = 0.09). No significant relationship was observed between minutes of MBSR(BC) practice and SSP or OSP. CONCLUSIONS: These data suggest that MBSR(BC) may be an efficacious treatment to improve objective and subjective sleep parameters in BCS.

Medical Subject Headings (MeSH)
ActigraphyAgedBreast NeoplasmsCarcinomaFemaleHumansMiddle AgedMindfulnessSelf ReportSleepSleep Initiation and Maintenance DisordersStress, PsychologicalTreatment Outcome
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations78
Citations/Year7.8
Relative Citation Ratio3.69
NIH Percentile88.9%
Research Impact Scores
APT Score0.95
Weight Score1.99
Normalized Score0.67
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