An anti-inflammatory diet as treatment for inflammatory bowel disease: a case series report.
Study Goal
The researchers aimed to evaluate the potential of the Anti-Inflammatory Diet (IBD-AID) as an adjunct dietary therapy for inflammatory bowel disease (IBD) by assessing symptom reduction and medication discontinuation.
Results Summary
The study found that 60% of patients had a good or very good response to the diet, with all 11 reviewed patients discontinuing at least one IBD medication and experiencing symptom reduction, including decreased bowel frequency. The mean Harvey Bradshaw Index (HBI) and Modified Truelove and Witts Severity Index (MTLWSI) scores significantly improved after the diet.
Population
40 patients with IBD (11 underwent detailed review: 8 with Crohn’s disease and 3 with ulcerative colitis, aged 19-70 years).
Effective Dosage
Not specified
Duration
4 or more weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Anti-Inflammatory Diet (IBD-AID) | decrease | disease | patients with IBD | - | had either a good or very good response | #1 |
Anti-Inflammatory Diet (IBD-AID) | decrease | medication use | 11 adult patients with IBD (8 with CD, 3 with UC) | 100% | were able to discontinue at least one of their prior IBD medications | #2 |
Anti-Inflammatory Diet (IBD-AID) | decrease | symptoms | 11 adult patients with IBD (8 with CD, 3 with UC) | - | had symptom reduction | #3 |
Anti-Inflammatory Diet (IBD-AID) | decrease | bowel frequency | 11 adult patients with IBD (8 with CD, 3 with UC) | - | had symptom reduction | #4 |
Anti-Inflammatory Diet (IBD-AID) | decrease | Harvey Bradshaw Index (HBI) | 11 adult patients with IBD (8 with CD, 3 with UC) | average decrease of 9.5 | decrease | #5 |
Anti-Inflammatory Diet (IBD-AID) | decrease | Modified Truelove and Witts Severity Index (MTLWSI) | 11 adult patients with IBD (8 with CD, 3 with UC) | average decrease of 7 | decrease | #6 |
BACKGROUND: The Anti-Inflammatory Diet (IBD-AID) is a nutritional regimen for inflammatory bowel disease (IBD) that restricts the intake of certain carbohydrates, includes the ingestion of pre- and probiotic foods, and modifies dietary fatty acids to demonstrate the potential of an adjunct dietary therapy for the treatment of IBD. METHODS: Forty patients with IBD were consecutively offered the IBD-AID to help treat their disease, and were retrospectively reviewed. Medical records of 11 of those patients underwent further review to determine changes in the Harvey Bradshaw Index (HBI) or Modified Truelove and Witts Severity Index (MTLWSI), before and after the diet. RESULTS: Of the 40 patients with IBD, 13 patients chose not to attempt the diet (33%). Twenty-four patients had either a good or very good response after reaching compliance (60%), and 3 patients' results were mixed (7%). Of those 11 adult patients who underwent further medical record review, 8 with CD, and 3 with UC, the age range was 19-70 years, and they followed the diet for 4 or more weeks. After following the IBD-AID, all (100%) patients were able to discontinue at least one of their prior IBD medications, and all patients had symptom reduction including bowel frequency. The mean baseline HBI was 11 (range 1-20), and the mean follow-up score was 1.5 (range 0-3). The mean baseline MTLWSI was 7 (range 6-8), and the mean follow-up score was 0. The average decrease in the HBI was 9.5 and the average decrease in the MTLWSI was 7. CONCLUSION: This case series indicates potential for the IBD-AID as an adjunct dietary therapy for the treatment of IBD. A randomized clinical trial is warranted.