Behavioural activation versus mindfulness-based guided self-help treatment administered through a smartphone application: a randomised controlled trial.
Study Goal
The researchers aimed to compare the effectiveness of smartphone-delivered behavioral activation (BA) and mindfulness treatments for major depressive disorder.
Results Summary
The study found no significant overall difference between BA and mindfulness treatments. However, BA was more effective for participants with higher initial depression severity, while mindfulness worked better for those with lower initial severity.
Population
Adults diagnosed with major depressive disorder (mean age 36.0 years).
Effective Dosage
Not specified (8-week program administered via smartphone application).
Duration
8 weeks, with a 6-month follow-up.
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
behavioural activation (BA) treatment | decrease | depression severity | participants with higher initial severity of depression | - | was more effective than | #1 |
mindfulness treatment | decrease | depression severity | participants with lower initial severity | - | worked better than | #2 |
behavioural activation (BA) treatment | no change | depression severity | participants diagnosed with major depressive disorder | - | did not differ significantly from | #3 |
mindfulness treatment | no change | depression severity | participants diagnosed with major depressive disorder | - | did not differ significantly from | #4 |
OBJECTIVES: Evaluating and comparing the effectiveness of two smartphone-delivered treatments: one based on behavioural activation (BA) and other on mindfulness. DESIGN: Parallel randomised controlled, open, trial. Participants were allocated using an online randomisation tool, handled by an independent person who was separate from the staff conducting the study. SETTING: General community, with recruitment nationally through mass media and advertisements. PARTICIPANTS: 40 participants diagnosed with major depressive disorder received a BA treatment, and 41 participants received a mindfulness treatment. 9 participants were lost at the post-treatment. INTERVENTION BA: An 8-week long behaviour programme administered via a smartphone application. Mindfulness: An 8-week long mindfulness programme, administered via a smartphone application. MAIN OUTCOME MEASURES: The Beck Depression Inventory-II (BDI-II) and the nine-item Patient Health Questionnaire Depression Scale (PHQ-9). RESULTS: 81 participants were randomised (mean age 36.0 years (SD=10.8)) and analysed. Results showed no significant interaction effects of group and time on any of the outcome measures either from pretreatment to post-treatment or from pretreatment to the 6-month follow-up. Subgroup analyses showed that the BA treatment was more effective than the mindfulness treatment among participants with higher initial severity of depression from pretreatment to the 6-month follow-up (PHQ-9: F (1, 362.1)=5.2, p<0.05). In contrast, the mindfulness treatment worked better than the BA treatment among participants with lower initial severity from pretreatment to the 6-month follow-up (PHQ-9: F (1, 69.3)=7.7, p<0.01); BDI-II: (F(1, 53.60)=6.25, p<0.05). CONCLUSIONS: The two interventions did not differ significantly from one another. For participants with higher severity of depression, the treatment based on BA was superior to the treatment based on mindfulness. For participants with lower initial severity, the treatment based on mindfulness worked significantly better than the treatment based on BA. TRIAL REGISTRATION: Clinical Trials NCT01463020.