Creatine supplementation and aging musculoskeletal health.
Study Goal
The researchers aimed to determine whether combining creatine supplementation with resistance training provides greater musculoskeletal benefits compared to resistance training alone in aging populations.
Results Summary
The meta-analyses indicated that creatine supplementation combined with resistance training positively affects aging muscle mass and upper body strength more than resistance training alone. Creatine also showed potential benefits for bone mineral density and bone biology.
Population
Aging individuals (specific age range not mentioned)
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Resistance training | increase | aging musculoskeletal health | - | - | produces several physiological adaptations which improve | #1 |
Resistance training | increase | muscle and bone mass and strength | - | - | increased | #2 |
creatine supplementation and resistance training | increase | aging muscle mass and upper body strength | - | - | has a positive effect on | #3 |
Creatine | increase | bone mineral density and indices of bone biology | - | - | shows promise for improving | #4 |
creatine supplementation and resistance training | increase | aging musculoskeletal health | - | - | could be an effective intervention to improve | #5 |
Sarcopenia refers to the progressive loss of muscle mass and muscle function and is a contributing factor for cachexia, bone loss, and frailty. Resistance training produces several physiological adaptations which improve aging musculoskeletal health, such as increased muscle and bone mass and strength. The combination of creatine supplementation and resistance training may further lead to greater physiological benefits. We performed meta-analyses which indicate creatine supplementation combined with resistance training has a positive effect on aging muscle mass and upper body strength compared to resistance training alone. Creatine also shows promise for improving bone mineral density and indices of bone biology. The combination of creatine supplementation and resistance training could be an effective intervention to improve aging musculoskeletal health.