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Anemia in pregnancy.

Clinics in laboratory medicine
June 1, 2013
Kari M Horowitz et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the role of iron in treating anemia during pregnancy, including its efficacy and alternative treatments for severe cases.

Results Summary

The study found that iron deficiency anemia accounts for 75% of anemias in pregnancy, with oral iron supplementation being the recommended treatment. Parenteral iron and erythropoietin are alternatives for severe or refractory cases.

Population

Pregnant individuals with anemia, particularly iron deficiency anemia.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Oral iron supplementation
decrease
iron deficiency anemia
in pregnancy
-
is the recommended treatment
#1
Parenteral iron
decrease
iron deficiency anemia
in severe or refractory cases in pregnancy
-
can also be used
#2
Erythropoietin
decrease
iron deficiency anemia
in severe or refractory cases in pregnancy
-
can also be used
#3
nutritional supplementation
decrease
other forms of inherited and acquired anemias
in pregnancy
-
include
#4
corticosteroids
decrease
other forms of inherited and acquired anemias
in pregnancy
-
include
#5
supportive transfusions
decrease
other forms of inherited and acquired anemias
in pregnancy
-
include
#6
splenectomy
decrease
other forms of inherited and acquired anemias
in pregnancy
-
include
#7
Abstract

Hemodynamic changes occur in pregnancy to prepare for expected blood loss at delivery. Physiologic anemia occurs in pregnancy because plasma volume increases more quickly than red cell mass. Anemia is most commonly classified as microcytic, normocytic, or macrocytic. Iron deficiency anemia accounts for 75% of all anemias in pregnancy. Oral iron supplementation is the recommended treatment of iron deficiency anemia in pregnancy. Parenteral iron and erythropoietin can also be used in severe or refractory cases. Outcomes and treatments for other forms of inherited and acquired anemias in pregnancy vary by disease, and include nutritional supplementation, corticosteroids, supportive transfusions, and splenectomy.

Medical Subject Headings (MeSH)
AnemiaFemaleHumansPregnancyPregnancy Complications, Hematologic
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations48
Citations/Year4.0
Relative Citation Ratio2.13
NIH Percentile76.5%
Research Impact Scores
APT Score0.75
Weight Score1.56
Normalized Score0.69
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