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Effects of macronutrient intake on thigh muscle mass during home-based walking training in middle-aged and older women.

Scandinavian journal of medicine & science in sports
October 1, 2013
K Okazaki et al. (8 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether post-exercise macronutrient supplementation enhances increases in skeletal muscle mass and strength during home-based interval walking training in middle-aged and older women.

Results Summary

The study found that post-exercise macronutrient supplementation significantly increased hamstring muscle tissue area (2.8% vs -1.0%) and isometric knee flexion force (16.3% vs 6.5%) compared to walking alone. These results suggest that supplementation partially enhances the benefits of interval walking training.

Population

Healthy middle-aged and older women (41-78 years).

Effective Dosage

Post-exercise macronutrient supplementation (7.6 g protein, 32.5 g carbohydrate, and 4.4 g fat) after each walking session.

Duration

5 months.

Interactions

None mentioned.

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
post-exercise macronutrient supplementation during a 5-month home-based interval walking training (IWT)
increase
skeletal muscle mass and strength
healthy middle-aged and older women
-
accelerated exercise-induced increases
#1
post-exercise macronutrient supplementation
increase
thigh muscle mass and strength
middle-aged and older women
-
enhanced the increases
#2
post-exercise macronutrient supplementation
increase
increase in hamstring muscle tissue area
NUT group
2.8 ± 1.2%
was significantly higher
#3
IWT alone
decrease
increase in hamstring muscle tissue area
CNT group
-1.0 ± 0.7%
was
#4
post-exercise macronutrient supplementation
increase
increase in isometric knee flexion force
NUT group
16.3 ± 3.7%
was significantly higher
#5
IWT alone
increase
increase in isometric knee flexion force
CNT group
6.5 ± 3.0%
was
#6
Abstract

We examined whether post-exercise macronutrient supplementation during a 5-month home-based interval walking training (IWT) accelerated exercise-induced increases in skeletal muscle mass and strength in healthy middle-aged and older women. Thirty-five women (41-78 years) were randomly divided into two groups: IWT alone (CNT, n = 18) or IWT plus post-exercise macronutrient (7.6 g protein, 32.5 g carbohydrate, and 4.4 g fat) supplementation (NUT, n = 17). For IWT, all subjects were instructed to repeat five or more sets of 3-min low-intensity walking at 40% peak aerobic capacity (Vo2 peak ), followed by a 3-min high-intensity walking above 70% Vo2 peak per day for 4 or more days per week. We determined Vo2 peak , thigh muscle tissue area by computer tomography, and thigh muscle strength in all subjects before and after IWT. We found that an increase in hamstring muscle tissue area was 2.8 ± 1.2% in NUT vs -1.0 ± 0.7% in CNT and that in isometric knee flexion force was 16.3 ± 3.7% in NUT vs 6.5 ± 3.0% in CNT; both were significantly higher in NUT than in CNT (both, P < 0.001). Thus, post-exercise macronutrient supplementation enhanced the increases in thigh muscle mass and strength, although partially, in home-based IWT in middle-aged and older women.

Medical Subject Headings (MeSH)
AdultAgedDietary CarbohydratesDietary FatsDietary ProteinsDietary SupplementsFemaleHumansJapanKnee JointMiddle AgedMuscle StrengthMuscle, SkeletalOxygen ConsumptionThighWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations16
Citations/Year1.3
Relative Citation Ratio0.74
NIH Percentile39.5%
Research Impact Scores
APT Score0.50
Weight Score1.50
Normalized Score0.70
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