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Value associated with mindfulness meditation and moderate exercise intervention in acute respiratory infection: the MEPARI Study.

Family practice
August 1, 2013
David Rakel et al. (7 authors)
Journal ArticleRandomized Controlled TrialResearch Support, N.I.H., ExtramuralHuman StudyClinical
Study Details

Study Goal

The researchers aimed to assess whether mindfulness meditation or exercise could reduce ARI-related costs and improve outcomes compared to a control group.

Results Summary

Meditation showed the greatest cost benefit, reducing total costs per subject to $65 compared to $214 for the control group, primarily through fewer missed work days. Exercise also reduced costs but less significantly, and both interventions improved ARI outcomes in incidence, duration, and severity.

Population

154 adults aged 50+ from Madison, WI during the 2009-10 cold/flu season.

Effective Dosage

Not specified

Duration

Duration of the cold/flu season (exact length not specified)

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
exercise
decrease
total cost per subject
adults ≥50 years
$136 (95% CI: $64-$232)
reduced
#1
meditation
decrease
total cost per subject
adults ≥50 years
$65 (95% CI: $34-$104)
reduced
#2
exercise
increase
medication costs
adults ≥50 years
$16.60
had the highest
#3
meditation
no change
medication costs
adults ≥50 years
$5.90
had
#4
meditation
increase
cost benefit
adults ≥50 years
-
had the greatest
#5
meditation
decrease
ARI-associated health-related costs
adults ≥50 years
-
add value
#6
exercise
decrease
ARI-associated health-related costs
adults ≥50 years
-
add value
#7
Abstract

BACKGROUND AND OBJECTIVES: Acute respiratory infection (ARI) is among the most common, debilitating and expensive human illnesses. The purpose of this study was to assess ARI-related costs and determine if mindfulness meditation or exercise can add value. METHODS: One hundred and fifty-four adults ≥50 years from Madison, WI for the 2009-10 cold/flu season were randomized to (i) wait-list control (ii) meditation or (iii) moderate intensity exercise. ARI-related costs were assessed through self-reported medication use, number of missed work days and medical visits. Costs per subject were based on cost of generic medications, missed work days ($126.20) and clinic visits ($78.70). Monte Carlo bootstrap methods evaluated reduced costs of ARI episodes. RESULTS: The total cost per subject for the control group was $214 (95% CI: $105-$358), exercise $136 (95% CI: $64-$232) and meditation $65 (95% CI: $34-$104). The majority of cost savings was through a reduction in missed days of work. Exercise had the highest medication costs at $16.60 compared with $5.90 for meditation (P = 0.004) and $7.20 for control (P = 0.046). Combining these cost benefits with the improved outcomes in incidence, duration and severity seen with the Meditation or Exercise for Preventing Acute Respiratory Infection study, meditation and exercise add value for ARI. Compared with control, meditation had the greatest cost benefit. This savings is offset by the cost of the intervention ($450/subject) that would negate the short-term but perhaps not long-term savings. CONCLUSIONS: Meditation and exercise add value to ARI-associated health-related costs with improved outcomes. Further research is needed to confirm results and inform policies on adding value to medical spending.

Medical Subject Headings (MeSH)
Acute DiseaseAmbulatory CareCost of IllnessCosts and Cost AnalysisExercise TherapyHumansMaleMedication AdherenceMeditationMiddle AgedMindfulnessOutcome Assessment, Health CareRespiratory Tract InfectionsSick LeaveTreatment OutcomeWaiting Lists
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations14
Citations/Year1.2
Relative Citation Ratio0.62
NIH Percentile33.3%
Research Impact Scores
APT Score0.50
Weight Score1.48
Normalized Score0.70
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