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Optimal nutrition for predialysis chronic kidney disease.

Advances in chronic kidney disease
March 1, 2013
Rebecca Filipowicz et al. (2 authors)
Journal ArticleResearch Support, N.I.H., ExtramuralReviewHuman Study
Study Details

Study Goal

The researchers aimed to determine whether dietary calcium restriction could minimize vascular calcification in advanced CKD patients.

Results Summary

The study suggested that dietary calcium restriction might help minimize vascular calcification in advanced CKD, but did not provide specific data on the magnitude of this effect.

Population

Patients with advanced chronic kidney disease (CKD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Moderate protein consumption along with a diet low in sodium
decrease
kidney disease progression
predialysis CKD
-
might slow
#1
Increasing vegetable protein intake
decrease
serum phosphorus
predialysis CKD
-
might decrease
#2
Increasing vegetable protein intake
decrease
uremic toxins
predialysis CKD
-
might decrease
#3
Increasing vegetable protein intake
decrease
kidney damage
predialysis CKD
-
might decrease
#4
dietary strategies targeting obesity
decrease
CKD progression
predialysis CKD
-
might also benefit
#5
dietary calcium and phosphorus restriction
decrease
vascular calcification
those with more advanced CKD
-
could minimize
#6
Dietary fiber and vitamin D supplementation
decrease
inflammation
CKD
-
might also be important to decrease
#7
Abstract

Diet potentially plays a major role in the progression and complications of predialysis CKD. Moderate protein consumption along with a diet low in sodium might slow kidney disease progression. Increasing vegetable protein intake might decrease serum phosphorus, uremic toxins, and kidney damage. Because obesity might be an important factor in the increasing prevalence of CKD, dietary strategies targeting obesity might also benefit CKD progression. In those with more advanced CKD, dietary calcium and phosphorus restriction could minimize vascular calcification. Dietary fiber and vitamin D supplementation might also be important to decrease inflammation in CKD.

Medical Subject Headings (MeSH)
AnimalsCalcium, DietaryDietary FatsDietary FiberDietary ProteinsDisease ProgressionEnergy IntakeGlomerular Filtration RateHumansPhosphorus, DietaryPlant Proteins, DietaryPotassium, DietaryRenal Insufficiency, ChronicSodium Chloride, DietaryVitamin D
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality65/10
Citation Metrics
Total Citations15
Citations/Year1.3
Relative Citation Ratio0.67
NIH Percentile35.9%
Research Impact Scores
APT Score0.50
Weight Score0.66
Normalized Score0.61
Related Supplements
Optimal nutrition for predialysis chronic kidney disease. | Panacea Index