Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies.
Study Goal
The researchers aimed to evaluate the cardiovascular benefits of moderate alcohol consumption, particularly focusing on the effects of different alcoholic beverages, including wine.
Results Summary
Moderate alcohol consumption, especially of polyphenol-rich beverages like wine and beer, showed cardiovascular protective effects in both healthy individuals and those with documented CVD. Red wine appeared to offer greater protection than spirits due to its higher polyphenolic content.
Population
Healthy subjects and patients with documented cardiovascular disease (CVD).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Heavy or binge alcohol consumption | increase | morbidity and mortality | - | - | unquestionably leads to increased | #1 |
moderate alcohol consumption | decrease | cardiovascular disease (CVD) | patients with documented CVD and even in healthy subjects | - | seems to confer cardiovascular protective effects | #2 |
alcoholic beverages rich in polyphenols, such as wine and beer | decrease | cardiovascular disease (CVD) | patients with documented CVD and even in healthy subjects | - | seems to confer cardiovascular protective effects | #3 |
wine and beer (but especially red wine) | decrease | cardiovascular disease (CVD) | - | - | seem to confer greater cardiovascular protection | #4 |
AIMS: The aim of this review was to focus on the knowledge of the cardiovascular benefits of moderate alcohol consumption, as well as to analyze the effects of the different types of alcoholic beverages. METHODS: Systematic revision of human clinical studies and meta-analyses related to moderate alcohol consumption and cardiovascular disease (CVD) from 2000 to 2012. RESULTS: Heavy or binge alcohol consumption unquestionably leads to increased morbidity and mortality. Nevertheless, moderate alcohol consumption, especially alcoholic beverages rich in polyphenols, such as wine and beer, seems to confer cardiovascular protective effects in patients with documented CVD and even in healthy subjects. CONCLUSIONS: In conclusion, wine and beer (but especially red wine) seem to confer greater cardiovascular protection than spirits because of their polyphenolic content. However, caution should be taken when making recommendations related to alcohol consumption.