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Update on nutrients involved in maintaining healthy bone.

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion
April 1, 2013
Mariangela Rondanelli et al. (4 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of calcium, along with other nutrients, in the prevention of osteoporosis and maintenance of bone health.

Results Summary

The abstract highlights calcium as a primary focus for nutritional prevention of osteoporosis but notes the importance of additional nutrients like vitamins B, C, K, and silicon for bone health. The efficacy of calcium is implied but not detailed, with further clinical studies suggested for conclusive evidence.

Population

Elderly individuals at risk for osteoporosis (implied but not explicitly stated).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
calcium and vitamin D
no change
nutritional prevention of osteoporosis
-
-
have been the primary focus
#1
vitamins B, C, K, and silicon
increase
proper maintenance of bone health
-
-
could be recommended
#2
long-chain polyunsaturated fatty acids, potassium, magnesium, copper, selenium, and strontium
no change
-
-
-
are not conclusive
#3
long-chain polyunsaturated fatty acids, potassium, magnesium, copper, selenium, and strontium
increase
-
in vitro and in animal models
-
are interesting and promising
#4
Abstract

Osteoporosis is a leading cause of morbidity and mortality in the elderly and influences quality of life, as well as life expectancy. Currently, there is a growing interest among the medical scientists in search of specific nutrients and/or bioactive compounds of natural origin for the prevention of disease and maintenance of bone health. Although calcium and vitamin D have been the primary focus of nutritional prevention of osteoporosis, a recent research has clarified the importance of several additional nutrients and food constituents. Based on this review of the literature, supplementation with vitamins B, C, K, and silicon could be recommended for proper maintenance of bone health, although further clinical studies are needed. The results of studies on long-chain polyunsaturated fatty acids, potassium, magnesium, copper, selenium, and strontium are not conclusive, although studies in vitro and in animal models are interesting and promising.

Medical Subject Headings (MeSH)
Amino AcidsAscorbic AcidFoodHumansMineralsOsteoporosisProteinsVitamin B ComplexVitamin K
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations22
Citations/Year1.8
Relative Citation Ratio0.90
NIH Percentile46.4%
Research Impact Scores
APT Score0.50
Weight Score9.87
Normalized Score0.66
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