A randomized trial of protein supplementation compared with extra fast food on the effects of resistance training to increase metabolism.
Study Goal
The researchers aimed to evaluate the effects of resistance training combined with increased energy intake or protein supplementation on lean body mass, resting metabolic rate, and cardiovascular risk factors.
Results Summary
Resistance training for 12 weeks increased resting metabolic rate and lean body mass similarly with either increased energy intake or protein supplementation, but the rise in RMR exceeded expectations based on lean mass gain. Fasting insulin and ApoB levels increased in the fast-food group, but long-term follow-up showed no sustained differences in RMR or body composition.
Population
24 healthy males aged 19-32 years.
Effective Dosage
33 g whey protein/day or 1350 kcal fast-food meal/day.
Duration
12 weeks (with 12-month follow-up).
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
resistance training combined with increased energy intake or protein-supplementation | increase | lean body-mass | healthy males (aged 19-32 years) | from 59.7 ± 4.3 kg to 61.8 ± 4.1 kg | increased | #1 |
resistance training combined with increased energy intake or protein-supplementation | increase | resting metabolic-rate (RMR) | healthy males (aged 19-32 years) | from 1787 ± 143 kcal/24 h to 1954 ± 187 kcal/24 h | increased | #2 |
resistance training combined with increased energy intake or protein-supplementation | increase | body weight | healthy males (aged 19-32 years) | from 75.1 ± 6.9 kg to 78.7 ± 7.2 kg | increased | #3 |
fast-food/day (1350 kcal, 41 g protein) | increase | fasting serum-insulin levels | healthy males (aged 19-32 years) | - | increased | #4 |
fast-food/day (1350 kcal, 41 g protein) | increase | ApoB | healthy males (aged 19-32 years) | from 0.691 ± 0.14 g/L to 0.768 ± 0.17 g/L | increased | #5 |
resistance training for 12 weeks | no change | RMR, body weight, total fat and lean body-masses | healthy males (aged 19-32 years) | - | did not differ from baseline | #6 |
resistance training | decrease | risk of obesity | - | - | could potentially decrease | #7 |
OBJECTIVE: To prospectively evaluate the effects of resistance training combined with increased energy intake or protein-supplementation on lean body-mass, resting metabolic-rate (RMR) and cardiovascular risk factors. METHODS: Twenty-four healthy males (aged 19-32 years) performed resistance exercise for 12 weeks aiming for at least 1 hour training-sessions 3 times a week. The participants were randomized to consume extra protein (33 g whey protein/day) or a meal of fast-food/day (1350 kcal, 41 g protein). Body-composition was measured with Dual-Energy X-ray Absorptiometry (DEXA) and RMR by indirect calorimetry. Fasting blood samples were drawn before and after the 3-month training period and after 12 months. RESULTS: The body weight increased from 75.1 ± 6.9 kg to 78.7 ± 7.2 kg (p < 0.0001), without differences between the groups. RMR increased from 1787 ± 143 kcal/24 h to 1954 ± 187 kcal/24 h (p < 0.0001, N = 24), which was more than expected from the increase in lean body-mass (increase from 59.7 ± 4.3 kg to 61.8 ± 4.1 kg p = 0.004). Fasting serum-insulin levels increased in the fast-food group compared with the extra-protein group (p = 0.03). ApoB increased from 0.691 ± 0.14 g/L to 0.768 ± 0.17 g/L, p = 0.004, in the fast-food group only. Long-term follow up after 12 months showed that RMR, body weight, total fat and lean body-masses did not differ from baseline (n = 19). CONCLUSIONS: Resistance training for 12 weeks increased RMR and lean body-mass similarly when based on either an increased energy-intake or protein supplement. However, the increase in RMR was higher than expected from the increase in lean body-mass. Thus resistance training could potentially decrease the risk of obesity by induction of increased RMR.