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Nutrition and the risk of stroke.

The Lancet. Neurology
January 1, 2012
Graeme J Hankey
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to determine whether dietary supplementation with calcium reduces the risk of stroke.

Results Summary

The study found that calcium supplementation does not reduce the risk of stroke, based on reliable evidence. Less reliable evidence suggests stroke prevention may be linked to broader dietary patterns rather than specific supplements.

Population

General population, with a focus on stroke risk factors across different life stages.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Poor nutrition in the first year of a mother's life
increase
stroke risk
individuals in later life
-
predispose
#1
Undernutrition in utero, infancy, childhood, and adulthood
increase
stroke risk
individuals in later life
-
predispose
#2
Overnutrition
increase
stroke risk
-
-
increases
#3
Overnutrition
increase
obesity, hypertension, hyperlipidaemia, and diabetes
-
-
accelerating the development
#4
dietary supplementation with antioxidant vitamins, B vitamins, and calcium
no change
stroke risk
-
-
does not reduce
#5
diets that are prudent, aligned to the Mediterranean or DASH (Dietary Approaches to Stop Hypertension) diets, low in salt and added sugars, high in potassium, and meet, but do not exceed, energy requirements
decrease
stroke
-
-
can be prevented
#6
vitamin D and marine omega-3 fatty acid supplementation
neutral
incidence of stroke
-
-
examining the effects
#7
Abstract

Poor nutrition in the first year of a mother's life and undernutrition in utero, infancy, childhood, and adulthood predispose individuals to stroke in later life, but the mechanism of increased stroke risk is unclear. Overnutrition also increases the risk of stroke, probably by accelerating the development of obesity, hypertension, hyperlipidaemia, and diabetes. Reliable evidence suggests that dietary supplementation with antioxidant vitamins, B vitamins, and calcium does not reduce the risk of stroke. Less reliable evidence suggests that stroke can be prevented by diets that are prudent, aligned to the Mediterranean or DASH (Dietary Approaches to Stop Hypertension) diets, low in salt and added sugars, high in potassium, and meet, but do not exceed, energy requirements. Trials in progress are examining the effects of vitamin D and marine omega-3 fatty acid supplementation on incidence of stroke. Future challenges include the need to improve the quality of evidence linking many nutrients, foods, and dietary patterns to the risk of stroke.

Medical Subject Headings (MeSH)
HumansMalnutritionNutritional StatusRisk FactorsStroke
Study Links
Quality Scores
SafetyNot Assessed
Efficacy20/10
Quality75/10
Citation Metrics
Total Citations75
Citations/Year5.8
Relative Citation Ratio2.40
NIH Percentile79.7%
Research Impact Scores
APT Score0.95
Weight Score1.51
Normalized Score0.43
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