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The validation of an active control intervention for Mindfulness Based Stress Reduction (MBSR).

Behaviour research and therapy
January 1, 2012
Donal G MacCoon et al. (11 authors)
Journal ArticleRandomized Controlled TrialResearch Support, N.I.H., ExtramuralValidation StudyHuman StudyClinical
Study Details

Study Goal

The researchers aimed to validate an active control condition (HEP) and compare the relative efficacy of Mindfulness-Based Stress Reduction (MBSR) to HEP, specifically testing mindfulness as an active ingredient.

Results Summary

MBSR reduced thermal pain ratings under mindfulness-related instruction but not HEP-related instruction. Both MBSR and HEP showed improvements in general distress, anxiety, hostility, and medical symptoms over time, but MBSR was no more effective than HEP in improving these outcomes.

Population

63 participants (31 in MBSR, 32 in HEP)

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Mindfulness Based Stress Reduction (MBSR)
decrease
thermal pain ratings
63 participants
η(2) = .18
led to reductions
#1
-
decrease
general distress
63 participants
η(2) = .09
significant improvements over time
#2
-
decrease
anxiety
63 participants
η(2) = .08
significant improvements over time
#3
-
decrease
hostility
63 participants
η(2) = .07
significant improvements over time
#4
-
decrease
medical symptoms
63 participants
η(2) = .14
significant improvements over time
#5
-
no change
general distress, anxiety, hostility, medical symptoms
63 participants
-
no effects
#6
Mindfulness Based Stress Reduction (MBSR)
no change
well-being
63 participants
-
is no more effective than a rigorous active control
#7
Abstract

Most of the extant literature investigating the health effects of mindfulness interventions relies on wait-list control comparisons. The current article specifies and validates an active control condition, the Health Enhancement Program (HEP), thus providing the foundation necessary for rigorous investigations of the relative efficacy of Mindfulness Based Stress Reduction (MBSR) and for testing mindfulness as an active ingredient. 63 participants were randomized to either MBSR (n = 31) or HEP (n = 32). Compared to HEP, MBSR led to reductions in thermal pain ratings in the mindfulness- but not the HEP-related instruction condition (η(2) = .18). There were significant improvements over time for general distress (η(2) = .09), anxiety (η(2) = .08), hostility (η(2) = .07), and medical symptoms (η(2) = .14), but no effects of intervention. Practice was not related to change. HEP is an active control condition for MBSR while remaining inert to mindfulness. These claims are supported by results from a pain task. Participant-reported outcomes (PROs) replicate previous improvements to well-being in MBSR, but indicate that MBSR is no more effective than a rigorous active control in improving these indices. These results emphasize the importance of using an active control condition like HEP in studies evaluating the effectiveness of MBSR.

Medical Subject Headings (MeSH)
AdultFemaleHumansMaleMeditationMiddle AgedPain MeasurementStress, PsychologicalTreatment Outcome
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality80/10
Citation Metrics
Total Citations192
Citations/Year14.8
Relative Citation Ratio7.57
NIH Percentile96.5%
Research Impact Scores
APT Score0.95
Weight Score1.67
Normalized Score0.62
Related Supplements
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