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Gluten-free diet in nonceliac disease.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
June 1, 2011
Khalil El-Chammas et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the use of a gluten-free diet (GFD) as a treatment for celiac disease and other medical conditions.

Results Summary

The study found that a GFD is commonly recognized as effective for celiac disease and has been investigated for other conditions, but the strength of evidence varies, with some conditions having weak existing evidence.

Population

Patients with celiac disease and other medical conditions (dermatitis herpetiformis, irritable bowel syndrome, neurologic disorders, rheumatoid arthritis, diabetes mellitus, HIV-associated enteropathy).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
gluten-free diet
decrease
celiac disease
-
-
is commonly recognized as the treatment
#1
gluten-free diet
decrease
dermatitis herpetiformis
-
-
has been investigated as a treatment option
#2
gluten-free diet
decrease
irritable bowel syndrome
-
-
has been investigated as a treatment option
#3
gluten-free diet
decrease
neurologic disorders
-
-
has been investigated as a treatment option
#4
gluten-free diet
decrease
rheumatoid arthritis
-
-
has been investigated as a treatment option
#5
gluten-free diet
decrease
diabetes mellitus
-
-
has been investigated as a treatment option
#6
gluten-free diet
decrease
HIV-associated enteropathy
-
-
has been investigated as a treatment option
#7
gluten-free diet
neutral
nonceliac diseases
-
-
future research may better define the benefits
#8
Abstract

A gluten-free diet (GFD) is commonly recognized as the treatment for celiac disease. It also has been investigated as a treatment option for other medical conditions, including dermatitis herpetiformis, irritable bowel syndrome, neurologic disorders, rheumatoid arthritis, diabetes mellitus, and HIV-associated enteropathy. The strength of the evidence for the use of a GFD in these nonceliac diseases varies, and future research may better define the benefits of a GFD for those conditions with weak existing evidence.

Medical Subject Headings (MeSH)
Arthritis, RheumatoidAutistic DisorderCeliac DiseaseDermatitis HerpetiformisDiabetes MellitusDiet, Gluten-FreeHIV EnteropathyHumansIrritable Bowel SyndromeNervous System Diseases
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality60/10
Citation Metrics
Total Citations27
Citations/Year1.9
Relative Citation Ratio0.97
NIH Percentile49.2%
Research Impact Scores
APT Score0.75
Weight Score1.15
Normalized Score0.60
Related Supplements
Gluten-free diet in nonceliac disease. | Panacea Index