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A systematic review of insomnia and complementary medicine.

Sleep medicine reviews
April 1, 2011
Jerome Sarris et al. (2 authors)
Journal ArticleResearch Support, Non-U.S. Gov'tReviewSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the effectiveness of massage as a CAM intervention for chronic insomnia through a systematic review of RCTs.

Results Summary

The study did not locate or include any RCTs on massage that met basic inclusion criteria, indicating a lack of sufficient evidence to assess its efficacy for chronic insomnia.

Population

Chronic insomnia patients (specific demographics not detailed).

Effective Dosage

Not available

Duration

Not available

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
acupressure
decrease
chronic insomnia
-
d=1.42-2.12
evidentiary support
#1
tai chi
decrease
chronic insomnia
-
d=0.22-2.15
evidentiary support
#2
yoga
decrease
chronic insomnia
-
d=0.66-1.20
evidentiary support
#3
acupuncture
no change
chronic insomnia
-
-
mixed evidence
#4
L-tryptophan
no change
chronic insomnia
-
-
mixed evidence
#5
herbal medicines such as valerian
no change
chronic insomnia
-
-
weak and unsupportive evidence
#6
Abstract

In concert with growing public interest in complementary and alternative medicine (CAM), these therapies and products have been increasingly studied over the past two decades for the treatment of sleep disorders. While systematic reviews have been conducted on acupuncture and valerian in the treatment of insomnia, to date no comprehensive review has been conducted on all major CAM treatments. We sought to address this via a rigorous systematic review of hypnotic CAM interventions, including herbal and nutritional medicine, acupuncture, acupressure, yoga, tai chi, massage, aromatherapy and homoeopathy. The electronic databases MEDLINE (PubMed), CINAHL, PsycINFO, and The Cochrane Library were accessed during late 2009 for CAM randomized controlled trials (RCTs) in the treatment of chronic insomnia. Sixty-four RCTs were identified, of which 20 studies involving eight CAM interventions met final inclusion criteria. Effect size calculations (where possible) and a quality control analysis using a modified Jadad scale were undertaken. Many RCTs lacked methodological rigor, and were commonly excluded due to small sample size or an inadequate control condition. Among the studies that met inclusion criteria, there was evidentiary support in the treatment of chronic insomnia for acupressure (d=1.42-2.12), tai chi (d=0.22-2.15), yoga (d=0.66-1.20), mixed evidence for acupuncture and L-tryptophan, and weak and unsupportive evidence for herbal medicines such as valerian. Surprisingly, studies involving several mainstream CAM therapies (e.g., homoeopathy, massage, or aromatherapy) were not located or did not meet basic inclusion criteria. If CAM interventions are to be considered as viable stand-alone or adjuvant treatments for sleep disorders, future researchers are urged to use acceptable methodology, including appropriate sample sizes and adequate controls. RCTs evaluating other untested CAM therapies such as massage, homoeopathy, or osteopathy are encouraged, as is the exploration of using CAM therapies adjuvantly with conventional therapies.

Medical Subject Headings (MeSH)
AdultAntidepressive Agents, Second-GenerationComplementary TherapiesHumansPlant ExtractsRandomized Controlled Trials as TopicSleep Initiation and Maintenance DisordersTryptophanValerian
Study Links
Quality Scores
SafetyNot Assessed
Quality65/10
Citation Metrics
Total Citations182
Citations/Year13.0
Relative Citation Ratio7.73
NIH Percentile96.6%
Research Impact Scores
APT Score0.95
Weight Score0.69
Normalized Score0.53
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