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Vitamin D in health and disease.

Photodermatology, photoimmunology & photomedicine
October 1, 2010
Matteo C LoPiccolo et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to determine whether sun avoidance and sunscreen use affect vitamin D levels and to provide recommendations for adequate vitamin D intake.

Results Summary

The study found that regular sunscreen use is not associated with vitamin D insufficiency, and adequate vitamin D intake is linked to reduced risks of various health issues, including bone fractures, certain cancers, and cardiovascular disease. Intentional UV exposure is discouraged as a means to obtain vitamin D.

Population

Patients at risk for vitamin D insufficiency (general population, with consideration of skin type).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
adequate vitamin D intake
decrease
falls
the elderly
-
is associated with decreased risk
#1
adequate vitamin D intake
decrease
bone fractures
the elderly
-
is associated with decreased risk
#2
adequate vitamin D intake
decrease
breast cancer risk
-
-
is associated with decreased risk
#3
adequate vitamin D intake
decrease
gastrointestinal cancer risk
-
-
is associated with decreased risk
#4
adequate vitamin D intake
decrease
cardiovascular disease
-
-
is associated with decreased risk
#5
adequate vitamin D intake
decrease
all cause mortality
-
-
is associated with decreased risk
#6
adequate vitamin D intake
decrease
diabetes
-
-
is associated with decreased risk
#7
adequate vitamin D intake
decrease
multiple sclerosis
-
-
is associated with decreased risk
#8
regular use of sunscreen
no change
vitamin D insufficiency
-
-
is not associated with
#9
Abstract

BACKGROUND/PURPOSE: Investigations have revealed that vitamin D plays an important role in many areas of health and disease. Questions over whether sun avoidance and sunscreen use will decrease vitamin D levels may concern clinicians when counseling patients at risk for vitamin D insufficiency. A review of the role of vitamin D in health and disease, the impact of photoprotection and skin type on vitamin D levels, and recommendations for adequate vitamin D intake is provided to aid clinicians in counseling patients regarding these issues. RESULTS: Review of the literature indicates that adequate vitamin D intake is associated with decreased risk of falls and bone fractures in the elderly, breast and gastrointestinal cancer risk, cardiovascular disease, and possibly all cause mortality, diabetes, and multiple sclerosis. While skin type does affect vitamin D levels, regular use of sunscreen is not associated with vitamin D insufficiency. CONCLUSIONS: Adequate intake of vitamin D is important for maintenance of good health, and may be achieved through diet and oral supplementation. Intentional or prolonged exposure to ultraviolet light should not be used as a means of obtaining vitamin D.

Medical Subject Headings (MeSH)
DietDietary SupplementsHumansNutrition PolicySunlightSunscreening AgentsVitamin D
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations36
Citations/Year2.4
Relative Citation Ratio1.25
NIH Percentile58.5%
Research Impact Scores
APT Score0.75
Weight Score1.25
Normalized Score0.69
Related Supplements
Vitamin D in health and disease. | Panacea Index